Three steroidal alkaloids from Buxus hildebrandtii (original) (raw)

Journal of Natural Products, 1989

h s m c r .-B u x n s sempewirens of Turkish origin has yielded two new steroidal alkaloids, (-)-0-acetyl-N-benzoylbuxidienine 111 and (+)-nor-16a-acetoxybuxabenidienine [Z]. The structures have been determined through spectroscopic studies.

New Steroidal Alkaloids from the Roots of Buxus sempervirens

Journal of Natural Products, 1997

Phytochemical studies on an EtOH-soluble extract of the roots of Buxus sempervirens of Turkish origin have resulted in the isolation of three new steroidal alkaloids, (+)-semperviraminol (1), (+)-buxamine F (2), and (+)-17-oxocycloprotobuxine (3), along with two known steroidal alkaloids, (+)-buxoxybenzamine (4) and (+)-buxapapillinine (5). The structures of 1-3 were elucidated with the aid of spectroscopic studies. Compounds 4 and 5 exhibited phytotoxic activity against Lemna minor.

New Triterpenoidal Alkaloids from Buxus hyrcana

Phytochemical studies on the methanolic extract of the leaves of Buxus hyrcana pojark, collected in Iran, have resulted in the isolation of two new triterpenoidal alkaloids, (+)-2α,16β ,31triacetylbuxiran (1), (+)-2α,16β ,31-triacetyl-9-11-dihydrobuxiran (2). Spectroscopic methods were used to elucidate the structures of these new natural products.

CHEMICAL CONSTITUENTS OF BUXUS SEMPERVZRENS

A new flavonoid glycoside 1 is isolated from the leaves ofBvurssnnpnvirrnr, and its structure is determined on the basis of spectral studies. It is the first flavonoid glycoside to be isolated from the genus BUXUJ. We also report the isolation of methyl syringate from this plant. The isolation and '3C-nmr spectra of buxpsiine and cyclomicrophylline A are also described. Buxus smpewims L. (Bwaceae) is widely distributed in Eurasia. The H 2 0 extracts of the plant find extensive use in the indigenous system of medicine for the treatment of many diseases (1). Previously, we have reported a number of new steroidal alkaloids and two known flavonoids isolated for the first time from the genus Blrxrrr (2-5). In the present paper, we describe the isolation and structure elucidation of a new flavonoid glycoside, galactobuxin {I], along with methyl syringate 121. The isolation and 13C

Alkaloids from the Leaves of Buxus papilosa

Journal of Natural Products, 1986

A new steroidal alkaloid, cycloxobuxoviricine (l), has been isolated from the leaves ofEuxupapihra and its structure determined by spectroscopic methods. Isolation and 13C-nmr spectrum of another alkaloid, buxaminol B (2), not previously reported from the leaves of this plant is also described. 109 2 EXPERIMENTAL GENERAL EXPERIMENTAL PROCEDURES.-M~SS spectra were recorded on a Varian MAT 3 12 double focusing mass spectrometer connected to DEC-PDP 11/34 computer system. The 'H-nmr spectra were recorded in CDCI, on Bruker AM-300 NMR spectrometer at 300 MHz, while the ',C-nmr spectra were recorded at 75 MHz. Chemical shifts are expressed in ppm. Ir spectra were recorded on a Jasco IRA-I infrared spectrometer. The uv spectra were recorded on Shimadzu UV 240 instrument. The optical rotation was determined with a Polartronic D instrument. PLANT MArERIAL.-The leaves of B. papiha were collected from the northern region of Pakistan by the Forest Institute, Peshawar. The plant was identified by Prof. S. Irtifaq Ali, Department of Botany, University of Karachi, and a voucher specimen has been deposited in the Department of Botany, University of Karachi.

CHEMICAL CONSTITUENTS OF BUXUS SEMPERVZRENS novel flavonoid glycoside

Three steroidal alkaloids from Buxus hildebrandtii (original) (raw)

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