Microparticles from preeclamptic women induce vascular hyporeactivity in vessels from pregnant mice through an overproduction of NO (original) (raw)

Abstract

Preeclampsia is associated with an increase of circulating levels of microparticles but their role in vascular dysfunction occurring during this disease is not understood yet.

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References (35)

  1. Report of the national high blood pressure education program working Group: report on high blood pressure in pregnancy. Am J Obstet Gynecol. 2002; 183(Suppl):S1-S22.
  2. Roberts J. Endothelial dysfunction in preeclampsia. Semin Reprod Endocrinol.1998; 16:5-15.
  3. Roberts JM, Redman CWG. Preeclampsia: more than pregnancy-induced hypertension. Lancet. 1993; 341:1447-1451.
  4. Lowe DT. Nitric oxide dysfunction in the pathophysiology of preeclampsia. Nitric Oxide. 2000; 4:441-458.
  5. Walsh SW, Vaughan JE, Wang Y, Roberts LJ, 2 nd . Placental isoprostane is significantly increased in preeclampsia. Faseb J. 2000; 14:1289-1296.
  6. Clark BA, Halvorson L, Sachs B, Epstein FH. Plasma endothelin levels in preeclampsia: elevation and correlation with uric acid levels and renal impairment. Am J Obstet Gynecol. 1992; 166(3):962-968.
  7. Barry OP, Pratico D, Lawson JA, FitzGerald GA. Transcellular activation of platelets and endothelial cells by bioactive lipids in platelet microparticles. J Clin Invest. 1997; 99:2118-2127.
  8. Zwaal RF, Schroit AJ. Pathophysiologic implications of membrane phospholipid asymmetry in blood cells. Blood. 1997; 89:1121-1132.
  9. VanWijk MJ, Nieuwland R, Boer K, van der Post JA, VanBavel E, Sturk A. Microparticle subpopulations are increased in preeclampsia: possible involvement in vascular dysfunction? Am J Obstet Gynecol. 2002; 187:450-456.
  10. VanWijk MJ, Svedas E, Boer K, Nieuwland R, VanBavel E, Kublickiene R. Isolated microparticles, but not whole plasma, from women with preeclampsia impair endothelium-dependent relaxation in isolated myometrial arteries from healthy pregnant women. Am J Obstet Gynecol. 2002; 187:1686-93.
  11. Meziani F, Tesse A, David E, Wangesteen R, Schneider F, Andriantsitohaina R. Shed membrane particles from preeclamptic women generate vascular wall inflammation and blunt vascular contractility. Am J Pathol, 2006; 169:1473-1483.
  12. Poston L, McCarthy AL, Ritter JM. Control of vascular resistance in the maternal and feto-placental arterial beds. Pharmacol Ther. 1995; 65(2):215-239.
  13. Brown MA, Lindheimer MD, de Swiet M, Van Assche A, Moutquin JM. The classification and diagnosis of the hypertensive disorders of pregnancy: statement from the International Society for the Study of Hypertension in Pregnancy (ISSHP). Hypertens Pregnancy. 2001; 20:IX-XIV.
  14. Hugel B, Zobairi F and Freyssinet JM. Measuring circulating cell-derived microparticles. J Thromb Haemost 2004; 2 (10):1846-1847.
  15. Mulsch A, Mordvintcev P, Bassenge E, Jung F, Clement B and Busse R. In vivo spin trapping of glyceryl trinitrate-derived nitric oxide in rabbit blood vessels and organs. Circulation. 1995; 92:1876-1882.
  16. Tesse A, Martinez MC, Hugel B, Chalupsky K, Muller CD, Meziani F, Mitolo- Chieppa D, Freyssinet JM, Andriantsitohaina R. Upregulation of Proinflammatory Proteins Through NF-{kappa}B Pathway by Shed Membrane Microparticles Results in Vascular Hyporeactivity. Arterioscler Thromb Vasc Biol. 2005; 25(12):2522-2527.
  17. Leik CE, Walsh SW. Neutrophils infiltrate resistance-sized vessels of subcutaneous fat in women with preeclampsia. Hypertension. 2004; 44:72-77.
  18. Dechend R, Viedt C, Muller DN, Ugele B, Brandes RP, Wallukat G, Park JK, Janke J, Barta P, Theuer J, Fiebeler A, Homuth V, Dietz R, Haller H, Kreuzer J, Luft FC. AT1 receptor agonistic antibodies from preeclamptic patients stimulate NADPH oxidase. Circulation. 2003; 107:1632-1639.
  19. Hubel CA. Oxidative stress in the pathogenesis of preeclampsia. Proc Soc Exp Biol Med. 1999; 222(3):222-235.
  20. Khalil RA, Granger JP. Vascular mechanisms of increased arterial pressure in preeclampsia: lessons from animal models. Am J Physiol Regul Integr Comp Physiol. 2002; 283(1):R29-45.
  21. Gonzalez-Quintero VH, Jimenez JJ, Jy W, Mauro LM, Hortman L, O'Sullivan MJ, Ahn Y. Elevated plasma endothelial microparticles in preeclampsia. Am J Obstet Gynecol. 2003; 189:589-593.
  22. Martinez MC, Tesse A, Zobairi F, Andriantsitohaina R. Shed membrane microparticles from circulating and vascular cells in regulating vascular function. Am J Physiol Heart Circ Physiol. 2005; 288:H1004-1009.
  23. VanWijk MJ VE, Sturk A, Nieuwland R. Microparticles in cardiovascular diseases. Cardiovasc Res. 2003; 59:277-287.
  24. Salvemini D, Misko TP, Masferrer JL, Seibert K, Currie MG, Needleman P. Nitric oxide activates cyclooxygenase enzymes. Proc Natl Acad Sci U S A. 1993; 90:7240-7244.
  25. Salvemini D, Manning PT, Zweifel BS, Seibert K, Connor J, Currie MG, Needleman P, Masferrer JL. Dual inhibition of nitric oxide and prostaglandin production contributes to the antiinflammatory properties of nitric oxide synthase inhibitors. J Clin Invest. 1995; 96:301-308.
  26. Bobadilla LR, Perez-Alvarez V, Bracho Valdes I, Lopez-Sanchez P. Effect of pregnancy on the roles of nitric oxide and prostaglandins in 5- hydroxytryptamine-induced contractions in rat isolated thoracic and abdominal aorta. Clin Exp Pharmacol Physiol. 2005; 32:202-209.
  27. Jonhson RD, Savodsky Y, Graham C, Anteby EY, Polakoski KL, Huang X, Nelson DM. The expression and activity of prostaglandin H synthase-2 is enhanced in trophoblast from women with preeclampsia. J Clin Endocrinol Metab 82:3059-3062, 1997.
  28. Stoclet JC, Martinez MC, Ohlmann P, Chasserot S, Schott C, Kleschyov AL, Schneider F, Andriantsitohaina R. Induction of NO-synthase and dual effects of NO and cyclo-oxygenase products in regulation of arterial contraction in human septic shock. Circulation. 1999; 100 : 107.
  29. Barry OP, Kazanietz MG, Pratico D, FitzGerald GA. Arachidonic acid in platelet microparticles up-regulates cyclooxygenase-2-dependent prostaglandin formation via a protein kinase C/mitogen-activated protein kinase-dependent pathway. J Biol Chem. 1999; 274:7545-7556.
  30. Walsh SW. Eicosanoids in preeclampsia. Prostaglandins Leukot Essent Fatty Acids. 2004; 70:223-232.
  31. Gluais P, Lonchampt M, Morrow JD, Vanhoutte PM, Feletou M. Acetylcholine-induced endothelium-dependent contractions in the SHR aorta: the Janus face of prostacyclin. British J. of Pharmacol. 2005; 146: 834-845.
  32. Pratico D, Lawson JA, FitzGerald GA. Cyclooxygenase-dependent formation of the isoprostane, 8-epi prostaglandin F2 alpha. J Biol Chem 1995; 270:9800- 9808.
  33. Cracowski JL. Isoprostanes: an emerging role in vascular physiology and disease? Chem Phys Lipids. 2004; 128:75-83.
  34. Habermehl DA, Janowiak MA, Vagnoni KE, Bird IM, Magness RR. Endothelial vasodilator production by uterine and systemic arteries. IV. Cyclooxygenase isoform expression during the ovarian cycle and pregnancy in sheep. Biol Reprod. 2000; 62(3):781-788.
  35. Nelson SH, Steinsland OS, Wang Y, Yallampalli C, Dong YL, Sanchez JM. Increased nitric oxide synthase activity and expression in the human uterine artery during pregnancy. Circ Res. 2000; 87(5):406-411.