Modeling a preference-based index for two condition-specific measures (asthma and overactive bladder) using a nonparametric Bayesian method (original) (raw)
Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research, 2014
Abstract
Conventionally, parametric models were used for health state valuation data. Recently, researchers started to explore the use of nonparametric Bayesian methods in this area. We present a nonparametric Bayesian model to estimate a preference-based index for two condition-specific five-dimensional health state classifications, one for asthma (five-dimensional Asthma Quality of Life Utility Index) and the other for overactive bladder (five-dimensional Overactive Bladder Quality of Life-Utility Index). Samples of 307 and 311 members of the UK general population valued 99 health states selected from a total of 3125 health states defined by each of the measures using the time trade-off technique. The article presents the results of the nonparametric model and compares it with the original model estimated using a conventional parametric random-effects model. The different methods are compared theoretically and in terms of empirical performance across the two data sets. It also reports the ...
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