A Salmonella Type Three Secretion Effector/Chaperone Complex Adopts a Hexameric Ring-Like Structure (original) (raw)

13 14 running title: SopB/SigE complex organizes in ring-like hexamers 15 16 JB Accepts, published online ahead of print on 17 November 2014 J. Bacteriol. Abstract 17 18 Many bacterial pathogens use Type Three Secretion System (T3SS) to inject virulence 19 factors, named effectors, directly into the cytoplasm of target eukaryotic cells. Most of the 20 T3SS components are conserved among plant and animal pathogens suggesting a common 21 mechanism of recognition and secretion of effectors. On the contrary no common motif is yet 22 33 to promote the specificity and efficiency of T3SS recognition. 34 35