Critical Residues for Structure and Catalysis in Short-chain Dehydrogenases/Reductases (original) (raw)

Structural Role of Conserved Asn179 in the Short-Chain Dehydrogenase/Reductase Scaffold

Kurt Berndt

Biochemical and Biophysical Research Communications, 2001

View PDFchevron_right

Short-chain dehydrogenases/reductases (SDR): the 2002 update

Jawed Shafqat

Chemico-Biological Interactions, 2003

View PDFchevron_right

Active Site Directed Mutagenesis of 3β/17β-Hydroxysteroid Dehydrogenase Establishes Differential Effects on Short-Chain Dehydrogenase/Reductase Reactions †

Kurt Berndt

Biochemistry, 1997

View PDFchevron_right

Apo and holo crystal structures of an NADP-dependent aldehyde dehydrogenase from Streptococcus mutans

S. Marchal

Journal of Molecular Biology, 1999

View PDFchevron_right

Structural Modeling Studies of Aldehyde Dehydrogenase X: Insights into Key Interactions in the Tetrameric Assembly of the Isoenzyme

Noreen Asim

Protein and Peptide …, 2011

View PDFchevron_right

Structure of 3–isopropylmalate dehydrogenase in complex with NAD+: ligand–induced loop closing and mechanism for cofactor specificity

Akihiko Yamagishi

Structure, 1994

View PDFchevron_right

Distinct Conformation-mediated Functions of an Active Site Loop in the Catalytic Reactions of NAD-dependent D-Lactate Dehydrogenase and Formate Dehydrogenase

Matthew Kimber

Journal of Biological Chemistry, 2005

View PDFchevron_right

Computational exploration of the medium-chain dehydrogenase/reductase superfamily

Linus Östberg

2017

View PDFchevron_right

Structural determinants of substrate specificity in aldehyde dehydrogenases

Hector Riveros-Rosas

Chemico-Biological Interactions, 2013

View PDFchevron_right

Crystallographic evidence for active-site dynamics in the hydrolytic aldehyde dehydrogenases. Implications for the deacylation step of the catalyzed reaction

Lilian González

Chemico-biological Interactions, 2011

View PDFchevron_right

The Crystal Structure of 3alpha -Hydroxysteroid Dehydrogenase/Carbonyl Reductase from Comamonas testosteroni Shows a Novel Oligomerization Pattern within the Short Chain Dehydrogenase/Reductase Family

Gerhard Klebe

Journal of Biological Chemistry, 2000

View PDFchevron_right

The Crystal Structure of A Ternary Complex of Betaine Aldehyde Dehydrogenase from Pseudomonas aeruginosa Provides New Insight into the Reaction Mechanism and Shows A Novel Binding Mode of the 2′-Phosphate of NADP+ and A Novel Cation Binding Site

OMAR BORRAYO RIVERA

Journal of Molecular Biology, 2009

View PDFchevron_right

Dual Coenzyme Specificity of Photosynthetic Glyceraldehyde-3-phosphate Dehydrogenase Interpreted by the Crystal Structure of A 4 Isoform Complexed with NAD † , ‡

Paolo Trost

Biochemistry, 2003

View PDFchevron_right

Crystal structure of NAD-dependent formate dehydrogenase

Boris Strokopytov

European Journal of Biochemistry, 1992

View PDFchevron_right

Crystallographic and solution studies of NAD(+)- and NADH-bound alkylhydroperoxide reductase subunit F (AhpF) from Escherichia coli provide insight into sequential enzymatic steps

Frank Eisenhaber

Biochimica et biophysica acta, 2015

View PDFchevron_right

Structure of L-3-hydroxyacyl-coenzyme A dehydrogenase: preliminary chain tracing at 2.8-A resolution

Jens Birktoft

View PDFchevron_right

Atomic Resolution Structures of R-specific Alcohol Dehydrogenase from Lactobacillus brevis Provide the Structural Bases of its Substrate and Cosubstrate Specificity

Dietmar Schomburg

Journal of Molecular Biology, 2005

View PDFchevron_right

Structural and mechanistic characteristics of dihydropteridine reductase: a member of the Tyr-(Xaa)3-Lys-containing family of reductases and dehydrogenases

Kottayil Varughese

Proceedings of the National Academy of Sciences, 1994

View PDFchevron_right

The structure of NADH in the enzyme dTDP-D-glucose dehydratase (RmIB)

Adrian Hegeman

Journal of the American Chemical Society, 2003

View PDFchevron_right

Structural basis for discrimination between oxyanion substrates or inhibitors in aspartate-β-semialdehyde dehydrogenase

Julio Blanco

Acta Crystallographica Section D-biological Crystallography, 2004

View PDFchevron_right

Crystal Structure of a Ternary Complex of Tritrichomonas foetus Inosine 5‘-Monophosphate Dehydrogenase: NAD + Orients the Active Site Loop for Catalysis † , ‡

Gregory Petsko

Biochemistry, 2002

View PDFchevron_right

The Crystal Structure of Escherichia coli Ketopantoate Reductase with NADP + Bound † , ‡

Carina Lobley

Biochemistry, 2005

View PDFchevron_right

Molecular Determinants of the Cofactor Specificity of Ribitol Dehydrogenase, a Short-Chain Dehydrogenase/Reductase

DR.RANJIT KUMAR SINGH

Applied and Environmental Microbiology, 2012

View PDFchevron_right

The Crystal Structure of Shikimate Dehydrogenase (AroE) Reveals a Unique NADPH Binding Mode

Duncan McRee

Journal of Bacteriology, 2003

View PDFchevron_right

The Structure of NADH in the Enzyme dTDP d -glucose Dehydratase (RmlB

Adrian Hegeman

Journal of The American Chemical Society, 2003

View PDFchevron_right

Crystallographic study of coenzyme, coenzyme analogue and substrate binding in 6-phosphogluconate dehydrogenase: implications for NADP specificity and the enzyme mechanism

Claire Naylor

Structure, 1994

View PDFchevron_right

Structure of a short-chain dehydrogenase/reductase fromBacillus anthracis

Wladek Minor

Acta Crystallographica Section F Structural Biology and Crystallization Communications, 2012

View PDFchevron_right

The role of substrate-binding groups in the mechanism of aspartate-β-semialdehyde dehydrogenase

Ronald Viola

Acta Crystallographica Section D Biological Crystallography, 2004

View PDFchevron_right

Structure and quantum chemical analysis of NAD+-dependent isocitrate dehydrogenase: Hydride transfer and co-factor specificity

Takashi Tamura

Proteins: Structure, Function, and Bioinformatics, 2007

View PDFchevron_right

Crystal Structure of Human Dihydrolipoamide Dehydrogenase: NAD+/NADH Binding and the Structural Basis of Disease-causing Mutations

Diana R Tomchick

Journal of Molecular Biology, 2005

View PDFchevron_right