Critical Residues for Structure and Catalysis in Short-chain Dehydrogenases/Reductases (original) (raw)
Structural Role of Conserved Asn179 in the Short-Chain Dehydrogenase/Reductase Scaffold
Kurt Berndt
Biochemical and Biophysical Research Communications, 2001
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Short-chain dehydrogenases/reductases (SDR): the 2002 update
Jawed Shafqat
Chemico-Biological Interactions, 2003
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Active Site Directed Mutagenesis of 3β/17β-Hydroxysteroid Dehydrogenase Establishes Differential Effects on Short-Chain Dehydrogenase/Reductase Reactions †
Kurt Berndt
Biochemistry, 1997
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Apo and holo crystal structures of an NADP-dependent aldehyde dehydrogenase from Streptococcus mutans
S. Marchal
Journal of Molecular Biology, 1999
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Structural Modeling Studies of Aldehyde Dehydrogenase X: Insights into Key Interactions in the Tetrameric Assembly of the Isoenzyme
Noreen Asim
Protein and Peptide …, 2011
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Structure of 3–isopropylmalate dehydrogenase in complex with NAD+: ligand–induced loop closing and mechanism for cofactor specificity
Akihiko Yamagishi
Structure, 1994
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Distinct Conformation-mediated Functions of an Active Site Loop in the Catalytic Reactions of NAD-dependent D-Lactate Dehydrogenase and Formate Dehydrogenase
Matthew Kimber
Journal of Biological Chemistry, 2005
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Computational exploration of the medium-chain dehydrogenase/reductase superfamily
Linus Östberg
2017
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Structural determinants of substrate specificity in aldehyde dehydrogenases
Hector Riveros-Rosas
Chemico-Biological Interactions, 2013
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Crystallographic evidence for active-site dynamics in the hydrolytic aldehyde dehydrogenases. Implications for the deacylation step of the catalyzed reaction
Lilian González
Chemico-biological Interactions, 2011
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The Crystal Structure of 3alpha -Hydroxysteroid Dehydrogenase/Carbonyl Reductase from Comamonas testosteroni Shows a Novel Oligomerization Pattern within the Short Chain Dehydrogenase/Reductase Family
Gerhard Klebe
Journal of Biological Chemistry, 2000
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The Crystal Structure of A Ternary Complex of Betaine Aldehyde Dehydrogenase from Pseudomonas aeruginosa Provides New Insight into the Reaction Mechanism and Shows A Novel Binding Mode of the 2′-Phosphate of NADP+ and A Novel Cation Binding Site
OMAR BORRAYO RIVERA
Journal of Molecular Biology, 2009
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Dual Coenzyme Specificity of Photosynthetic Glyceraldehyde-3-phosphate Dehydrogenase Interpreted by the Crystal Structure of A 4 Isoform Complexed with NAD † , ‡
Paolo Trost
Biochemistry, 2003
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Crystal structure of NAD-dependent formate dehydrogenase
Boris Strokopytov
European Journal of Biochemistry, 1992
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Crystallographic and solution studies of NAD(+)- and NADH-bound alkylhydroperoxide reductase subunit F (AhpF) from Escherichia coli provide insight into sequential enzymatic steps
Frank Eisenhaber
Biochimica et biophysica acta, 2015
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Structure of L-3-hydroxyacyl-coenzyme A dehydrogenase: preliminary chain tracing at 2.8-A resolution
Jens Birktoft
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Atomic Resolution Structures of R-specific Alcohol Dehydrogenase from Lactobacillus brevis Provide the Structural Bases of its Substrate and Cosubstrate Specificity
Dietmar Schomburg
Journal of Molecular Biology, 2005
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Structural and mechanistic characteristics of dihydropteridine reductase: a member of the Tyr-(Xaa)3-Lys-containing family of reductases and dehydrogenases
Kottayil Varughese
Proceedings of the National Academy of Sciences, 1994
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The structure of NADH in the enzyme dTDP-D-glucose dehydratase (RmIB)
Adrian Hegeman
Journal of the American Chemical Society, 2003
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Structural basis for discrimination between oxyanion substrates or inhibitors in aspartate-β-semialdehyde dehydrogenase
Julio Blanco
Acta Crystallographica Section D-biological Crystallography, 2004
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Crystal Structure of a Ternary Complex of Tritrichomonas foetus Inosine 5‘-Monophosphate Dehydrogenase: NAD + Orients the Active Site Loop for Catalysis † , ‡
Gregory Petsko
Biochemistry, 2002
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The Crystal Structure of Escherichia coli Ketopantoate Reductase with NADP + Bound † , ‡
Carina Lobley
Biochemistry, 2005
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Molecular Determinants of the Cofactor Specificity of Ribitol Dehydrogenase, a Short-Chain Dehydrogenase/Reductase
DR.RANJIT KUMAR SINGH
Applied and Environmental Microbiology, 2012
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The Crystal Structure of Shikimate Dehydrogenase (AroE) Reveals a Unique NADPH Binding Mode
Duncan McRee
Journal of Bacteriology, 2003
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The Structure of NADH in the Enzyme dTDP d -glucose Dehydratase (RmlB
Adrian Hegeman
Journal of The American Chemical Society, 2003
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Crystallographic study of coenzyme, coenzyme analogue and substrate binding in 6-phosphogluconate dehydrogenase: implications for NADP specificity and the enzyme mechanism
Claire Naylor
Structure, 1994
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Structure of a short-chain dehydrogenase/reductase fromBacillus anthracis
Wladek Minor
Acta Crystallographica Section F Structural Biology and Crystallization Communications, 2012
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The role of substrate-binding groups in the mechanism of aspartate-β-semialdehyde dehydrogenase
Ronald Viola
Acta Crystallographica Section D Biological Crystallography, 2004
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Structure and quantum chemical analysis of NAD+-dependent isocitrate dehydrogenase: Hydride transfer and co-factor specificity
Takashi Tamura
Proteins: Structure, Function, and Bioinformatics, 2007
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Crystal Structure of Human Dihydrolipoamide Dehydrogenase: NAD+/NADH Binding and the Structural Basis of Disease-causing Mutations
Diana R Tomchick
Journal of Molecular Biology, 2005
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