Insulin, androgens, and obesity in women with and without polycystic ovary syndrome: a heterogeneous group of disorders (original) (raw)

1999, Fertility and Sterility

To analyze the correlations among insulin, androgens, body mass index (BMI), and other related metabolic anomalies in women with and without polycystic ovary syndrome (PCOS). Design: Retrospective study of normal and obese women with and without PCOS. Setting: Gynecologic endocrinology units of Elche, San Juan, and Alicante Hospitals and Hormone Laboratory at Alicante University Hospital ("Miguel Hernández" University). Patient(s): A total of 212 women were studied: 137 with PCOS and 75 without PCOS. Intervention(s): BMI, gonadotropins, insulin, androgens (T, androstenedione, DHEAS), 17␣-hydroxyprogesterone, sex hormone-binding globulin, and triglycerides were studied. Glycemia and insulin response to the tolerance test (GTT) with a 100-g oral glucose load were also assessed in 103 women.

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