G protein-coupled receptor heteromers as new targets for drug development (original) (raw)

The impact of G-protein-coupled receptor hetero-oligomerization on function and pharmacology

Marco Scarselli

FEBS Journal, 2005

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G Protein-Coupled Receptor Oligomerization Revisited: Functional and Pharmacological Perspectives

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Pharmacological Reviews, 2014

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Functional Significance of Oligomerization of G-protein-coupled Receptors

Michel Bouvier

2000

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Structural and functional aspects of G protein-coupled receptor oligomerization

T. Hebert, Michel Bouvier

Biochemistry and Cell Biology, 1998

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Oligomerization Domains of G Protein-Coupled Receptors

Harel Weinstein

Contemporary Clinical Neuroscience, 2005

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Dimerization and oligomerization of G-protein-coupled receptors: debated structures with established and emerging functions

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The Journal of endocrinology, 2008

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Oligomerization of G Protein-Coupled Receptors: Past, Present, and Future †

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Biochemistry, 2004

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Influence of oligomerization on the dynamics of G-protein coupled receptors as assessed by normal mode analysis

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Proteins-structure Function and Bioinformatics, 2008

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Oligomerization of G-protein-coupled transmitter receptors

Michel Bouvier

Nature reviews. Neuroscience, 2001

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G Protein-Coupled Receptor Heterodimerization in the Brain

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G Protein Coupled Receptors: Trafficking and Oligomerization, 2013

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Basic Pharmacological and Structural Evidence for Class A G-Protein-Coupled Receptor Heteromerization

Gemma Navarro

Frontiers in pharmacology, 2016

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G Protein-Coupled Receptor Multimers: A Question Still Open Despite the Use of Novel Approaches

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Molecular pharmacology, 2015

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Basic concepts in G-protein-coupled receptor homo-and heterodimerization

Enric I. Canela

…, 2007

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Molecular determinants of GPCR oligomerization

aditya kumar

GPCRs, 2020

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Dimers of G-Protein Coupled Receptors as Versatile Storage and Response Units

Floyd Sallee

International Journal of Molecular Sciences, 2014

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Oligomerization of opioid receptors

lakshmi devi

Methods, 2002

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Biochemical and biophysical demonstration of GPCR oligomerization in mammalian cells

Michel Bouvier

Life Sciences, 2001

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A heterodimer-selective agonist shows in vivo relevance of G protein-coupled receptor dimers

Jennifer Whistler

Proceedings of the National Academy of Sciences, 2005

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G protein-coupled receptor oligomerization provides the framework for signal discrimination

Marco Parenti

Journal of Neurochemistry, 2007

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G protein-coupled receptor hetero-dimerization: contribution to pharmacology and function

Kjell Fuxe

British Journal of Pharmacology, 2009

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Selectivity, Cooperativity, and Reciprocity in the Interactions between the -Opioid Receptor, Its Ligands, and G-proteins

Victor Hruby

Journal of Biological Chemistry, 2004

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Revolution in GPCR signalling: opioid receptor heteromers as novel therapeutic targets: IUPHAR review 10

Lakshmi Devi

British journal of pharmacology, 2014

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GPCR homomers and heteromers: A better choice as targets for drug development than GPCR monomers?

Enric I. Canela

Pharmacology & …, 2009

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G Protein-Coupled Receptor Transactivation

Kim Jonas

Methods in Cell Biology, 2013

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GPCR Heteromers and their Allosteric Receptor-Receptor Interactions

Dasiel Oscar Borroto-Escuela, Amina Woods, Current Medicinal Chemistry, Diego Guidolin

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Heterotrimeric G proteins precouple with G protein-coupled receptors in living cells

Amy Benians

Proceedings of the National Academy of Sciences, 2005

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Visualization and ligand-induced modulation of dopamine receptor dimerization at the single molecule level

Alina Tabor

Scientific Reports, 2016

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International Union of Basic and Clinical Pharmacology. LXVII. Recommendations for the Recognition and Nomenclature of G Protein-Coupled Receptor Heteromultimers

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Pharmacological Reviews, 2007

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G Protein-Coupled Receptor Heteromerization: A Role in Allosteric Modulation of Ligand Binding

Kai Ye

Molecular Pharmacology, 2011

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G-protein-coupled receptor heteromers: function and ligand pharmacology

Enric I. Canela

British journal of pharmacology, 2008

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G Protein-Coupled Receptor Oligomerization: Implications for G Protein Activation and Cell Signaling

Gerda Breitwieser

Circulation Research, 2004

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