The class I histone deacetylases of the platyhelminth parasite Schistosoma mansoni (original) (raw)

Identification of novel multi-stage histone deacetylase (HDAC) inhibitors that impair Schistosoma mansoni viability and egg production

Giuliana Papoff

Parasites & Vectors

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Schistosoma mansoni histone acetyltransferase GCN5: linking histone acetylation to gene activation

Marcelo Fantappié, Luiz Juliano

Molecular and Biochemical Parasitology, 2004

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Crystal structures of Schistosoma mansoni histone deacetylase 8 reveal a novel binding site for allosteric inhibitors

Giuliana Papoff

Journal of Biological Chemistry

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Histone methylation changes are required for life cycle progression in the human parasite Schistosoma mansoni

Ronaldo de Carvalho Augusto

PLOS Pathogens

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Control of transcription in Schistosoma mansoni: Chromatin remodeling and other regulatory elements

Daniel Furtado

Acta Tropica, 2008

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Fluorescence-based screening assays for the NAD⁺-dependent histone deacetylase smSirt2 from Schistosoma mansoni

Wolfgang Sippl, Christophe Romier

Journal of biomolecular screening, 2015

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Molecular basis for the antiparasitic activity of a mercaptoacetamide derivative that inhibits histone deacetylase 8 (HDAC8) from the human pathogen schistosoma mansoni

Wolfgang Sippl

Journal of molecular biology, 2014

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Histone Methylome of the Human Parasite Schistosoma Mansoni

Ronaldo de Carvalho Augusto

RNA Technologies

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Measuring Histone Modifications in the Human Parasite Schistosoma mansoni

Ronaldo de Carvalho Augusto

Methods in molecular biology, 2020

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Epigenetic control of gene function in schistosomes: a source of therapeutic targets?

Alejandro Cabezas-cruz

Frontiers in Genetics, 2014

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Towards an understanding of the epigenetics of schistosomes: a comparative epigenomic study

Christoph Grunau

Memórias do Instituto Oswaldo Cruz, 2011

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Histone deacetylase inhibitors induce apoptosis, histone hyperacetylation and up-regulation of gene transcription in Schistosoma mansoni

Christoph Grunau

Molecular and Biochemical Parasitology, 2009

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Schistosoma mansoni: Developmental arrest of miracidia treated with histone deacetylase inhibitors

Christoph Grunau

Experimental Parasitology, 2009

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The Epigenome of Schistosoma mansoni Provides Insight about How Cercariae Poise Transcription until Infection

Marion A L Picard

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Histone deacetylase enzymes as potential drug targets in cancer and parasitic diseases

Federico Camicia

Journal of biomedicine & biotechnology, 2006

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Histone acetyltransferases and deacetylase in Entamoeba histolytica

Carol A Gilchrist

Molecular and biochemical parasitology, 2004

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Pharmacological inhibition of lysine-specific demethylase 1 (LSD1) induces global transcriptional deregulation and ultrastructural alterations that impair viability in Schistosoma mansoni

Teresa Borrello

2019

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Native chromatin immunoprecipitation (N-ChIP) and ChIP-Seq of Schistosoma mansoni: Critical experimental parameters

Christoph Grunau

Molecular and Biochemical Parasitology, 2009

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A Novel Class of Schistosoma mansoni Histone Deacetylase 8 (HDAC8) Inhibitors Identified by Structure-Based Virtual Screening and In Vitro Testing

Conrad Simoben

Molecules (Basel, Switzerland), 2018

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Exposure to hycanthone alters chromatin structure around specific gene functions and specific repeats in Schistosoma mansoni

David Roquis, Julie Lepesant, Christoph Grunau

Frontiers in Genetics, 2014

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Theileria annulata histone deacetylase 1 (TaHDAC1) initiates schizont to merozoite stage conversion

Gordon Langsley

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Epigenetic Changes Modulate Schistosome Egg Formation and Are a Novel Target for Reducing Transmission of Schistosomiasis

Eduardo Torres

PLoS Pathogens, 2014

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Probing the elusive catalytic activity of vertebrate class IIa histone deacetylases

Sergio Serafini, Paola Gallinari

Bioorganic & Medicinal Chemistry Letters, 2008

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Quantitative chromatin immunoprecipitation (Q-ChIP) applied to Schistosoma mansoni

Raymond Pierce

Molecular and Biochemical Parasitology, 2009

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Dissecting the Biological Functions of Drosophila Histone Deacetylases by RNA Interference and Transcriptional Profiling

Enrico Cundari

Journal of Biological Chemistry, 2006

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Transcriptional changes in Schistosoma mansoni during early schistosomula development and in the presence of erythrocytes

Tran Tuyet Mai

PLoS neglected tropical diseases, 2010

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