Structural features of the pore formed by Staphylococcus aureus α-toxin inferred from chemical modification and primary structure analysis (original) (raw)

1992, FEMS Microbiology Letters

AI-generated Abstract

This study investigates the structural features of the pore formed by Staphylococcus aureus α-toxin, utilizing chemical modification and primary structure analysis. The findings reveal critical insights into the role of histidine residues in membrane interaction and functionality. The research contributes to a deeper understanding of α-toxin's mechanism of action, potentially aiding in the development of therapeutic strategies against S. aureus infections.

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