Obesity and the skin: Skin physiology and skin manifestations of obesity (original) (raw)
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A Hospital-Based Clinical Study of Cutaneous Changes in Overweight and Obesity
https://www.ijhsr.org/IJHSR\_Vol.7\_Issue.6\_June2017/IJHSR\_Abstract.09.html, 2017
Background: Obesity has been considered as one of the major epidemics of 21 st century due to its detrimental effects on homeostatic milieu of the body. Not only internal organ systems but externally our so called external barrier, skin, also gets involved. Objectives: To present a descriptive study regarding varied cutaneous manifestations in overweight (BMI=25 Kg/m 2-29.99 Kg/m 2) and obese (BMI=/> 30 Kg/m 2) population along with their prevalence in both overweight and different grades of obesity. Materials and methods: A cross-sectional descriptive study was conducted on 300 overweight and obese individuals, enrolled from dermatology outpatient clinic on the basis of BMI. A thorough physical and cutaneous examination of all the enrolled patients was performed by a trained dermatologist and all the cutaneous changes were noted down along with their demographic and clinical details on a set proforma. The study was approved by Institutional Review Board. Results: Out of 300 patients, 65(21.67%) were males and 235(78.33%) were females. Majority of the patients belonged to grade 1 obesity i.e. 52.67% whereas least no. of patients were of grade 3 obesity (3.33%). Acanthosis nigricans was the most commonest cutaneous change (74.67%) followed by cellulite (68%), and rogenetic alopecia (55.67%), acrochordons (46%), striae distensae (44.33%)and infections (43%). Acanthosis nigricans was leading in all the three grades of obesity with 100% involvement in grade 3 obesity. Similarly, acrochordons, keratosis pilaris, hirsutism, acne vulgaris, androgenetic alopecia, striae distensae, peizogenic pedal papules, cellulite, hidradenitis suppurativa, intertrigo, infections and psoriasis were also more common in grade 3 obesity. Conclusion: A myriad of cutaneous changes have been seen in obesity. These changes may simply have cosmetic implications for patients, but for a clinician these serve as reflection of metabolic imbalance occurring internally.
Dermatological manifestations of obesity
Journal of Pakistan Association of Dermatology, 2016
Objective To determine the frequency of various cutaneous manifestations in patients with obesity and correlate these skin changes with the grades of obesity. Patients and methods The study was conducted at Departments of Medicine and Dermatology, Sir Syed College of Medical Sciences and Hospital Karachi from 1 st January 2014 till 30 th June 2014. Patients belonging to both sexes and different age groups having body mass index (BMI) > 25kg/m 2 with cutaneous manifestations of obesity were enrolled. Patients with skin changes secondary to other systemic illnesses, pregnancy and drugs were excluded. After an informed consent, demographic details, height and weight were documented. A clinical dermatological diagnosis was established after a detailed history and examination. Appropriate investigations were performed where required. Results 196 patients, 76 males (39%) and 120 females (61%) completed the study. Mean age was 43.6 + 10.8 years, age range being 19-70 years. Mean BMI 34 ...
Cutaneous manifestations in obesity
Journal of Pakistan Association of Dermatology, 2016
Objective To study the frequency of various dermatoses in obese patients and their comparison with the control group of normal weight individuals. Methods The duration of study was one year starting from March 2011 to March 2012. A total of 93 obese (BMI >30kg/m 2 ) and 93 normal weight (BMI 18.5-24.9 kg/m 2 ) individuals were included in the study. All the individuals underwent a complete medical and dermatological evaluation. All of them were evaluated for the presence of metabolic syndrome, as well. Results Common dermatoses seen in obese patients were acanthosis nigricans, striae, acrochordons, and various infections. Out of these acanthosis nigricans, acrochordons and striae had statistically significant relationship with obesity as compared to control group ( p <0.05). All the manifestations were also compared for diabetes, dyslipidemia and metabolic syndrome. Conclusion Obesity is associated significantly with certain dermatoses. Understanding and thorough knowledge of ...
Cutaneous manifestations associated with obesity
2016
Objective To study the frequency of cutaneous manifestations of obesity and their association with severity of disease in Pakistani population. Methods 100 outdoor patients visiting Rawal Institute of Health Sciences, Islamabad were studied during a period from May 2014 to July 2015. BMI was calculated by measuring weight in kilogram divided by square in height in meter. Cutaneous manifestations in obese patients with class I (CI) [BMI >30-34.9Kg/m2] and class II (CII) [BMI 35-39Kg/m2] disease were recorded. Results The mean age was 41.85±8.61 years while the mean BMI was 33.51±2.51 kg/m2. A significant difference for diabetes mellitus, striae and acanthosis nigricans was seen between CI and CII groups ( p <0.05). BMI showed significant positive correlation with DM ( r =0.280, p =0.005) and acne ( r =0.315, p =0.001) while diabetes mellitus showed with acanthosis nigricans ( r =0.373; p =0.000) and skin tags ( r =0.218, p =0.029). Acne showed with miliaria ( r =0.210, p =0.036...
VIMS Health Science Journal
Background: Obesity is a global epidemic. Obesity is associated with a number of dermatoses, including acanthosis nigricans, skin tag, keratosis pilaris, hyperandrogenism and hirsutism, striae distensae, and adiposis dolorosa. Objective: To elucidate the various skin changes in obesity and to determine if it is considered as an obesity marker. Methodology: 100 patients, aged 18 years or above satisfying the inclusion and exclusion criteria were drawn for a period of 18 months. Results: Out of 100 patients 54% were female, in their third and fourth decade. By occupation most of the females were housewives (40%) and the majority of males were farmers (14%). Type 2 diabetes mellitus was the most common systemic illness (24%). Pseudoacanthosis nigricans was the most prevalent skin change. 51% of patients had skin tags. 48% had striae distensae as a skin change. 10.86% male and 14.81% female patients had stasis dermatitis, 6% had leg venulectasias and 2% had leg ulcer. 26% had plantar hy...