Lignan bis-glucosides from Galium sinaicum (original) (raw)

This study reports the isolation and characterization of two new lariciresinol-based lignan bis-glucosides from the early fractions of the n-butanol extract of Galium sinaicum roots. The identified compounds, namely 7S, SR, 8'R-(-)-lariciresinol-4,4'-bis-O-\u03b2-D-glucopyranoside and 7S, 8R, 8'R-(-)-5-methoxylariciresinol-4,4'-bis-O-\u03b2-D-glucopyranoside, along with (-)-syringaresinol-4,4'-bis-O-\u03b2-D-glucopyranoside, were characterized using various spectroscopic methods, confirming their glucosidic structure. These findings expand the knowledge of the non-anthraquinone constituents of Galium sinaicum and provide insights into their structural properties.