Pharmacological studies of Glycyrrhiza glabra- a review (original) (raw)

Glycyrrhiza glabra, also known as liquorice and sweetwood, is native to the Mediterranean and certain areas of Asia. Historically, the dried rhizome and root of this plant were used medicinally by the Egyptian, Chinese, Greek, Indian and Roman civilizations as carminative, expectorant and cough remedies. It is now known that glycyrrhizic acid and its aglycone glycyrrhetinic acid present in the root extract are responsible for the biological activities. In modern medicine, liquorice extracts are employed as parenteral preparation for Chronic Hepatitis, Ulcer, viral infection and some common diseases. In Japan, it is used as pharmaceutical preparation since, 1960 years. In the present context glycyrrhizin and its derivative is focus on pharmacological studies, against disease viz. HIV syndrome, Hepatitis, H1N1 flue, cancer and diabetes etc.

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