An introduction to matrikines: extracellular matrix-derived peptides which regulate cell activity (original) (raw)

This article introduces matrikines, derived from the extracellular matrix, as key regulators of cellular activity, highlighting their role in modulating cell functions through interaction with specific receptors. Various examples of matrikines, including elastin-derived peptides and collagen-derived domains, are discussed regarding their implications in tumor invasion and potential anti-tumor properties, suggesting the extracellular matrix's significance extends beyond structural support to active cellular communication.