New monoclonal anti-human Fc gamma receptor II antibodies induce platelet aggregation (original) (raw)

Indirect evidence for a Fc gamma receptor on guinea pig platelets: Guinea pig represents a promising species for the investigation of human disorders with immune platelet activation

Patrick Menu

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The Role of the Human Fc Receptor FcγRIIA in the Immune Clearance of Platelets: A Transgenic Mouse Model

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Red cell sequestration during high dose intravenous immunoglobulin in idiopathic thrombocytopenic purpura

Elizabeth Macintyre

Blut, 1986

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C-terminal peptide of thrombospondin-1 induces platelet aggregation through the Fc receptor gamma -chain-associated signaling pathway and by agglutination

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Blood, 2001

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Journal of Clinical Investigation, 2008

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Monoclonal Antibodies to Platelet Glycoprotein IIb/IIIa as Antithrombotic Agentsa

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Identification and Characterization of Anti-Platelet Antibodies in Idiopathic Thrombocytopenic Purpura Patients

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Evidence that a 210,000-molecular-weight glycoprotein (GP 210) serves as a platelet Fc receptor

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Journal of Clinical Investigation, 1987

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Flow cytometric analysis of anti-platelet antibodies in idiopathic thrombocytopenic purpura

Roberto Reverberi

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Soluble Fc gamma receptor III in human plasma originates from release by neutrophils

Dirk Roos

The Journal of clinical investigation, 1990

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Nature of a Platelet-Agglutinating Factor in Serum of Patients with Idiopathic Thrombocytopenic Purpura*

Jack Levin

Journal of Clinical Investigation, 1963

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FcγRII mediates platelet aggregation caused by disintegrins and GPIIb/IIIa monoclonal antibody, AP2

Tur-fu Huang

Experimental Hematology, 2008

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A single-institution, 20-year prospective experience with an affordable Fc-receptor blockade method to treat patients with chronic, refractory autoimmune thrombocytopenic purpura

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Revista de investigación clínica; organo del Hospital de Enfermedades de la Nutrición

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Developing recombinant HPA-1a–specific antibodies with abrogated Fcγ receptor binding for the treatment of fetomaternal alloimmune thrombocytopenia

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Journal of Clinical Investigation, 2008

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Endothelial cell activation by immunoglobulins from patients with immune thrombocytopenic purpura or with antiphospholipid syndrome

Philippe Moerloose

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Involvement of Fcα/μ Receptor in IgM Anti-Platelet, but Not Anti-Red Blood Cell Autoantibody Pathogenicity in Mice

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Single amino acid mutation of FCγ receptor is associated with the development of heparin-induced thrombocytopenia

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British Journal of Haematology, 1995

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Thrombopenic purpura induced by a monoclonal antibody directed to a 35-kilodalton surface protein (p35) expressed on murine platelets and endothelial cells

Eduardo Rocha

Experimental Hematology, 2001

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Fc Receptor-mediated Platelet Activation Is Dependent on Phosphatidylinositol 3-Kinase Activation and Involves p120cbl

Abdel Saci

Journal of Biological Chemistry, 1999

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Low platelet counts alone do not cause bleeding in an experimental immune thrombocytopenic purpura in mice

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Patient autoantibodies induce platelet destruction signals via raft-associated glycoprotein Ib and Fc RIIa in immune thrombocytopenia

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5 Inhibitory and activating human antiplatelet antibodies

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Baillière's Clinical Haematology, 1998

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A murine monoclonal antibody that completely blocks the binding of fibrinogen to platelets produces a thrombasthenic-like state in normal platelets and binds to glycoproteins IIb and/or IIIa

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Journal of Clinical Investigation, 1983

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Binding of plasma factor XIII to thrombin-receptor activated human platelets

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Thrombosis and Haemostasis, 2009

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A subset of anti-HLA antibodies induces FcγRIIa-dependent platelet activation

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Thrombotic thrombocytopenic purpura plasma enhances platelet–leucocyte interaction in vitro

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Detection of Antiplatelet Antibody in Immune Thrombocytopenic Purpura

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Immune Thrombocytopenic Purpura as a Hemorrhagic Versus Thrombotic Disease: An Updated Insight into Pathophysiological Mechanisms

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Heparin-induced thrombocytopenia: mechanism of interaction of the heparin-dependent antibody with platelets

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Physical Proximity and Functional Interplay of the Glycoprotein Ib-IX-V Complex and the Fc Receptor FcγRIIA on the Platelet Plasma Membrane

wendy foss

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The influence of therapeutic blocking of Gp IIb/IIIa on platelet α-granular fibrinogen

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