Energetic Contributions to Channel Gating of Residues in the Muscle Nicotinic Receptor Î²1 Subunit (original) (raw)

Role of Pairwise Interactions between M1 and M2 Domains of the Nicotinic Receptor in Channel Gating

Guillermo Spitzmaul

Biophysical Journal, 2007

Initial Coupling of Binding to Gating Mediated by Conserved Residues in the Muscle Nicotinic Receptor

The Journal of General Physiology, 2005

Unmasking coupling between channel gating and ion permeation in the muscle nicotinic receptor

eLife, 2021

Subunit-Selective Contribution to Channel Gating of the M4 Domain of the Nicotinic Receptor

Carmen Esandi

Biophysical Journal

An Intersubunit Trigger of Channel Gating in the Muscle Nicotinic Receptor

Journal of Neuroscience, 2007

Bridging the Gap between Structural Models of Nicotinic Receptor Superfamily Ion Channels and Their Corresponding Functional States

Claudio Grosman

2010

Properties of the human muscle nicotinic receptor, and of the slow-channel myasthenic syndrome mutant epsilonL221F, inferred from maximum likelihood fits

David Beeson

The Journal of Physiology, 2003

Principal pathway coupling agonist binding to channel gating in nicotinic receptors

Nature, 2005

Nicotinic Receptor M3 Transmembrane Domain: Position 8' Contributes to Channel Gating

Guillermo Spitzmaul

Molecular Pharmacology, 2002

Gating at the Mouth of the Acetylcholine Receptor Channel: Energetic Consequences of Mutations in the αM2-Cap

Huibert D. Mansvelder

PLoS ONE, 2008

Binding to Gating Transduction in Nicotinic Receptors: Cys-Loop Energetically Couples to Pre-M1 and M2-M3 Regions

Journal of Neuroscience, 2009

An Intersubunit Hydrogen Bond in the Nicotinic Acetylcholine Receptor That Contributes to Channel Gating

Kristin Gleitsman

Journal of Biological Chemistry, 2008

Molecular basis of the two nonequivalent ligand binding sites of the muscle nicotinic acetylcholine receptor

P. Blount

Neuron, 1989

One-microsecond molecular dynamics simulation of channel gating in a nicotinic receptor homologue

Marc Delarue, Marc Baaden

Proceedings of the National Academy of Sciences, 2010

Invariant Aspartic Acid in Muscle Nicotinic Receptor Contributes Selectively to the Kinetics of Agonist Binding

The Journal of General Physiology, 2004

On the nature of partial agonism in the nicotinic receptor superfamily

David Colquhoun

Nature, 2008

Nicotinic Receptor Fourth Transmembrane Domain: Hydrogen Bonding by Conserved Threonine Contributes to Channel Gating Kinetics

Francisco J Barrantes, Steven m. M Sine

The Journal of General Physiology, 2000

Targeted molecular dynamics study of C-loop closure and channel gating in nicotinic receptors

PLoS Computational Biology, 2005

Energy and Structure of the M2 Helix in Acetylcholine Receptor-Channel Gating

Archana Jha

Biophysical Journal, 2009

A gating mechanism proposed from a simulation of a human 7 nicotinic acetylcholine receptor

Richard Henchman

Proceedings of the National Academy of Sciences, 2005

Role of the extracellular transmembrane domain interface in gating and pharmacology of a heteromeric neuronal nicotinic receptor

Mar Castillo

Journal of Neurochemistry, 2010

Β-Structure in the Membrane-Spanning Part of the Nicotinic Acetylcholine Receptor (Or How Helical Are Transmembrane Helices?)

Andreas Strecker

Trends in Biochemical Sciences, 1994

Myasthenic nicotinic receptor mutant interpreted in terms of the allosteric model

Stuart Edelstein

Comptes Rendus de l'Académie des Sciences - Series III - Sciences de la Vie, 1997

The Nicotinic Acetylcholine Receptor, A Model of Ligand-Gated Ion Channels

Jean-luc Galzi

The Jerusalem Symposia on Quantum Chemistry and Biochemistry, 1992

Probing the Effects of Residues Located Outside the Agonist Binding Site on Drug-Receptor Selectivity in the Nicotinic Receptor

Henry Lester

ACS Chemical Biology, 2012

Molecular tuning of fast gating in pentameric ligand-gated ion channels

Stuart Edelstein

Proceedings of the National Academy of Sciences, 2005

Interactions between loop 5 and β-strand β6' are involved in α7 nicotinic acetylcholine receptors channel gating

Mar Castillo

Journal of Neurochemistry, 2007

Determinants of Nicotinic Receptor Gating in Natural and Unnatural Side Chain Structures at the M2 9′ Position

Henry Lester

Neuron, 1996

The dissociation of acetylcholine from open nicotinic receptor channels

Proceedings of the National Academy of Sciences, 2001

Control of cation permeation through the nicotinic receptor channel

PLoS Computational Biology, 2005

A Re-Examination of Adult Mouse Nicotinic Acetylcholine Receptor Channel Activation Kinetics

The Journal of Physiology, 1999

Sources of energy for gating by neurotransmitters in acetylcholine receptor channels

Proceedings of the National Academy of Sciences, 2012

The intrinsic energy of the gating isomerization of a neuromuscular acetylcholine receptor channel

The Journal of General Physiology, 2012

Nicotinic Receptor Transduction Zone: Invariant Arginine Couples to Multiple Electron-Rich Residues

Biophysical Journal, 2013