Involvement of protein kinase Cζ in interleukin-1β induction of ADAMTS-4 and type 2 nitric oxide synthase via NF-κB signaling in primary human osteoarthritic chondrocytes
Edward Lavallie
Arthritis & Rheumatism, 2007
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ADAMTS-9 is synergistically induced by interleukin-1β and tumor necrosis factor α in OUMS-27 chondrosarcoma cells and in human chondrocytes
Toshitaka Oohashi
Arthritis & Rheumatism, 2005
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ADAMTS9 activation by interleukin 1β via NFATc1 in OUMS-27 chondrosarcoma cells and in human chondrocytes
Toshitaka Oohashi, Kursat O Yaykasli
Molecular and Cellular Biochemistry, 2009
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Interleukin-1β induced nuclear factor-κB binds to a disintegrin-like and metalloproteinase with thrombospondin type 1 motif 9 promoter in human chondrosarcoma cells
Gonul Erden
Molecular Medicine Reports, 2015
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Regulation of the human ADAMTS-4 promoter by transcription factors and cytokines
Srinivasan Thirunavukkarasu
Biochemical and Biophysical Research Communications, 2006
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IGF-1 and PDGF-bb suppress IL-1β-induced cartilage degradation through down-regulation of NF-κB signaling: Involvement of Src/PI-3k/AKT pathway
Prof. Dr. Mehdi Shakibaei
PLoS ONE, 2011
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Adaptor Proteins and Ras Synergistically Regulate IL-1-Induced ADAMTS-4 Expression in Human Chondrocytes
Mushtaq Ahmad
The Journal of Immunology, 2009
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NF-κB and MAPKs are involved in resistin caused ADAMTS-5 induction in Human Chondrocytes
Kursat O Yaykasli
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Augmentation of ADAMTS9 gene expression by IL-1 β is reversed by NF κ B and MAPK inhibitors, but not PI3 kinase inhibitors
sümeyya akyol
Cell Biochemistry and Function, 2012
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T Cell Factor 4 Is a Pro-catabolic and Apoptotic Factor in Human Articular Chondrocytes by Potentiating Nuclear Factor κB Signaling
Marcel Karperien
Journal of Biological Chemistry, 2013
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The modulation of matrix metalloproteinase and ADAM gene expression in human chondrocytes by interleukin-1 and oncostatin M: A time-course study using real-time quantitative reverse transcription-polymerase chain reaction
Dylan Edwards
Arthritis & Rheumatism, 2002
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Protein Kinase Cζ Is Up-regulated in Osteoarthritic Cartilage and Is Required for Activation of NF-κB by Tumor Necrosis Factor and Interleukin-1 in Articular Chondrocytes
Manas Majumdar
Journal of Biological Chemistry, 2006
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Potent Inhibition of the Master Chondrogenic FactorSox9 Gene by Interleukin-1 and Tumor Necrosis Factor-α
Benoit de Crombrugghe
Journal of Biological Chemistry, 2000
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Inhibition of ADAMTS-7 and ADAMTS-12 degradation of cartilage oligomeric matrix protein by alpha-2-macroglobulin
Mary Goldring
Osteoarthritis and Cartilage, 2008
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c-Maf Transcription Factor Regulates ADAMTS-12 Expression in Human Chondrogenic Cells
Paul di cesare
CARTILAGE, 2013
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Leptin induces ADAMTS-4, ADAMTS-5, and ADAMTS-9 genes expression by mitogen-activated protein kinases and NF-ĸB signaling pathways in human chondrocytes
Kursat O Yaykasli, 0mer faruk hatipoglu, Kubra Yildirim, Esra Gunduz
Cell Biology International, 2014
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T Cell Factor 4 Is a Pro-catabolic and Apoptotic Factor in Human Articular Chondrocytes by Potentiating Nuclear Factor B Signaling
Janine Post
Journal of Biological Chemistry, 2013
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ADAM-12 (meltrin α) is involved in chondrocyte proliferation via cleavage of insulin-like growth factor binding protein 5 in osteoarthritic cartilage
Atsuko Sehara
Arthritis & Rheumatism, 2008
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ADAMTS-9 in Mouse Cartilage Has Aggrecanase Activity That Is Distinct from ADAMTS-4 and ADAMTS-5
Karena Last
International Journal of Molecular Sciences, 2019
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A novel role for suppressor of cytokine signaling 3 in cartilage destruction via induction of chondrocyte desensitization toward insulin-like growth factor
Ruben Smeets
Arthritis & Rheumatism, 2006
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Immortalized human adult articular chondrocytes maintain cartilage-specific phenotype and responses to interleukin-1β
Mary Goldring
Arthritis & Rheumatism, 2000
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Cyclin-Dependent Kinase 9 Inhibition Protects Cartilage From the Catabolic Effects of Proinflammatory Cytokines
Jasper Yik, Zi'ang Hu
Arthritis & Rheumatology, 2014
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Basal and IL-1β enhanced chondrocyte chemotactic activity on monocytes are co-dependent on both IKKα and IKKβ NF-κB activating kinases
Stefania D'Adamo
Scientific Reports, 2021
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Role of Interleukin 6 (IL-6)/IL-6R-Induced Signal Tranducers and Activators of Transcription and Mitogen-Activated Protein Kinase/Extracellular Signal-Related Kinase in Upregulation of Matrix Metalloproteinase and ADAMTS Gene Expression in Articular Chondrocytes
Jean-Pierre Pujol
2005
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The increased synthesis of inducible nitric oxide inhibits IL-1ra synthesis by human articular chondrocytes: possible role in osteoarthritic cartilage degradation
Pierre Ranger
Osteoarthritis and Cartilage, 1996
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Distinct Effect of TCF4 on the NFκB Pathway in Human Primary Chondrocytes and the C20/A4 Chondrocyte Cell Line
Marcel Karperien
CARTILAGE, 2014
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Activation of NF-κB in Synovium versus Cartilage from Patients with Advanced Knee Osteoarthritis: A Potential Contributor to Inflammatory Aspects of Disease Progression
Henrik Druid
Journal of immunology (Baltimore, Md. : 1950), 2018
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Tumor necrosis factor ? activation of the apoptotic cascade in murine articular chondrocytes is associated with the induction of metalloproteinases and specific pro-resorptive factors
Cory Edgar
Arthritis & Rheumatism, 2003
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Double-knockout of ADAMTS-4 and ADAMTS-5 in mice results in physiologically normal animals and prevents the progression of osteoarthritis
Manas Majumdar
Arthritis & Rheumatism, 2007
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Mediation of interleukin-1?-induced transforming growth factor ?1 expression by activator protein 4 transcription factor in primary cultures of bovine articular chondrocytes: Possible cooperation with activator protein 1
Jean-Pierre Pujol
Arthritis & Rheumatism, 2003
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Protein kinase R plays a pivotal role in oncostatin M and interleukin-1 signalling in bovine articular cartilage chondrocytes
Sophie Gilbert
European Cells and Materials, 2012
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