A recurrent nasopharyngeal carcinoma with lacrimal sac involvement: A case report (original) (raw)
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Nasopharyngeal carcinoma presented as cavernous sinus tumour
PubMed, 2011
A 32 year Libyan male presented with the complaints of headache and diplopia. He was diagnosed with a cavernous sinus meningioma on the basis of MRI findings but no initial biopsy was taken. Depending on the radiologic diagnosis the patient was treated with gamma knife surgery twice, abroad. During follow up he developed left ear deafness and left cervical lymph adenopathy. An ENT evaluation with biopsy from the nasopharynx and cervical lymph node was taken. The histopathologic diagnosis of the resected tumour showed a nasopharyngeal carcinoma with cervical lymph node metastasis (poorly differentiated lympho-epithelial carcinoma). The cavernous sinus tumour which was initially treated as a meningioma was in fact metastasis from the nasopharyngeal carcinoma, making this an interesting and rare occurrence.
A clinicopathological study of masses of nasal cavity paranasal sinuses and nasopharynx
International Journal of Otorhinolaryngology and Head and Neck Surgery, 2017
Background: A variety of inflammatory, non neoplastic and neoplastic masses involving nasal cavity, paranasal sinuses and nasopharynx are commonly encountered in ENT clinics. The objective was to study the demographic profile, clinical presentation, radiological findings and its correlation with the histopathological findings of masses of nasal cavity, paranasal sinuses and nasopharynx. Methods: The study was conducted on patients having sinonasal and nasopharyngeal masses admitted in dept of ENT, GMC, Patiala from August 2014 to July 2016. The study was designed to evaluate demographic distribution, clinicopathological features, radiological findings of sinonasal and nasopharyngeal masses and to evaluate the correlation of clinical and radiological findings with histopathological diagnosis. Results: Analysis of 50 cases of masses in nasal cavity, paranasal sinuses and nasopharynx was done. Male to female ratio was 1.38:1. The commonest site was nasal cavity followed by paranasal sinuses. Nasal polyp was the most common non-neoplastic lesion. Among the neoplastic lesions studied, inverted papilloma was the most common benign lesion and squamous cell carcinoma was the most common malignant lesion observed. Conclusions: For proper evaluation of sinonasal and nasopharyngeal masses, clinical, radiological and histopathological evaluation should be done in all patients. Although radiology provides a road map to endoscopic surgeons for any existing or impending complications but histopathology always gives a confirmatory diagnosis.
A rare presentation of nasopharyngeal mass: a case report
International Journal of Otorhinolaryngology and Head and Neck Surgery, 2024
A Thornwaldt's cyst develops in the nasopharynx, which is the region where the throat and nasal passageways converge, extending from the back of the nasal tube to above the soft palate. A painful throat, obstruction of the eustachian tube, and pus with an unpleasant taste and odour might result from an infection of the cyst. Here in our study, we report a case of a 27-year-old male presented with symptoms of nasal obstruction and voice change for the past 1 year. On zero-degree endoscopic examination, a nasopharyngeal mass was seen arising from the roof of the nasopharynx without bony erosion of skull base. Further based on his radiological investigations, heterogeneous hyperintense lesion in T1/T2 weighted images of size 5×5 mm noted in nasopharynx most likely to be the Thornwaldt’s cyst. Thus, the surgical removal of the nasopharyngeal mass has been performed through a transoral and trans nasal endoscopic technique with no remnants at the surgical site. The histopathological findings revealed respiratory-type epithelium with underlying lymphoid tissue confirming Thornwald’s cyst as diagnosis. The patient was discharged with no complications and have been periodically advised for a follow-up. The differential diagnosis should include a meningocele or meningo-encephalocele. Various therapeutic approaches, including endoscopic, transoral, or trans palatal surgical interventions, can be used for treatment of symptomatic cysts.
Neoplastic masses of nasal cavity, paranasal sinuses, and nasopharynx: A clinicopathological study
Asian Pacific Journal of Health Sciences
Neoplastic masses were predominantly present in males with male:female ratio of 1.6:1 [Tables 1 and 2]. Clinical Presentation Neoplastic masses of nasal cavity, paranasal sinuses, and nasopharynx presented with nasal obstruction, epistaxis, nasal mass, and paranasal sinus swelling as shown in Table 3. Benign Masses Hemangioma was the most common among benign masses with the incidence of 42.8% (6 cases). It was present in all age group predominantly with male: female ratio of 2:1. Histopathological examination showed well-defined but uncapsulated lobules. Lobule was composed of capillary-sized, thin-walled, bloodfilled vessels, surrounded by a layer of pericytes, separated by connective tissue stroma [Figure 1]. The second most common mass observed in our study was inverted papilloma with an incidence of 35.7% primarily in 4 th and 5 th decades. Histopathological findings showed inverted growth pattern of proliferating columnar epithelium [Figure 2]. Angiofibroma was seen in males only in 2 nd decade of life with the incidence of 14% (2 cases), Histopathologically, there was the presence of mixture of fibrous stroma and blood vessels. Hematoma was seen in 1 male of 48 years age [Table 1]. Malignant Masses Squamous cell carcinoma was predominant among malignant mass with the incidence of 70% (7 cases), with a peak age of presentation in 6 th and 7 th decades with male:female ratio of 1.3:1. Histopathology showed cells forming sheets and nest of keratin pearls. Other malignant tumors were transition cell carcinoma, olfactory neuroblastoma, and non-Hodgkin's lymphoma. Each had an incidence of 10% (1 case). Age of presentation was 5 th and
The Egyptian Journal of Otolaryngology, 2019
Recurrence of nasopharyngeal carcinoma (NPC) is still a worrying issue despite the advent and advancement of treatment strategies. Presentation of recurrent NPC is different from primary NPC and indicates poor prognosis. Frontal sinus metastasis without any involvement of other sinuses is very rare and could be mistaken as sinusitis or mucocele. Owing to its rare occurrence, it presents a great challenge for clinicians to make a prompt diagnosis. The background chronic rhinosinusitis symptoms as a result of irradiation for NPC may masquerade the underlying paranasal sinus recurrence.