The Homeobox Genes MSX2 and MOX2 are Candidates for Regulating Epithelial–Mesenchymal Cell Interactions in the Human Placenta (original) (raw)

Placenta, 2000

Abstract

Homeobox genes of the Msx and Mox families are coexpressed in the vertebrate embryo in regions of epithelial–mesenchymal interactions. Here we show that a member of each family is expressed in extra-embryonic structures where epithelial and mesenchymal cell layers contact. In situ hybridization studies on first trimester human placental sections reveal that MSX2 and MOX2 are expressed predominantly in the

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