Involvement of Heme in the Degradation of Iron-regulatory Protein 2 (original) (raw)

Increased IRP1 and IRP2 RNA binding activity accompanies a reduction of the labile iron pool in HFE-expressing cells

Kenneth Blemings, Caroline Enns

Journal of Cellular Physiology, 2002

Post-transcriptional regulation of cellular iron homeostasis

Inactivation of Both RNA Binding and Aconitase Activities of Iron Regulatory Protein-1 by Quinone-induced Oxidative Stress

Journal of Biological Chemistry, 1999

Redox control of iron regulatory proteins

Redox Report, 2002

Human Cytoplasmic Aconitase (Iron Regulatory Protein 1) Is Converted into Its [3Fe-4S] Form by Hydrogen Peroxide in Vitro but Is Not Activated for Iron-responsive Element Binding

Jean-marc Moulis

Journal of Biological Chemistry, 1999

Insights on Regulation and Function of the Iron Regulatory Protein 1 (IRP1)*

Hemoglobin, 2008

Cellular Iron Metabolism – The IRP/IRE Regulatory Network

Ricky Joshi

2012

7. Iron regulatory proteins

Cellular regulation of the iron-responsive element binding protein: disassembly of the cubane iron-sulfur cluster results in high-affinity RNA binding

Proceedings of the National Academy of Sciences of the United States of America, 1992

INSIGHTS ON REGULATION AND FUNCTION OF THE IRON REGULATORY PROTEIN 1 (IRP1) Regulation and Function of IRP1

Iron regulatory protein-1 and -2: transcriptome-wide definition of binding mRNAs and shaping of the cellular proteome by iron regulatory proteins

Mayka Sánchez

Blood, 2011

Modulation of Cellular Iron Metabolism by Hydrogen Peroxide. EFFECTS OF H2O2 ON THE EXPRESSION AND FUNCTION OF IRON-RESPONSIVE ELEMENT-CONTAINING mRNAs IN B6 FIBROBLASTS

Journal of Biological Chemistry, 2001

Iron-regulatory proteins, iron-responsive elements and ferritin mRNA translation

Jack Rogers

The International Journal of Biochemistry & Cell Biology, 1999

Iron-responsive degradation of iron-regulatory protein 1 does not require the Fe–S cluster

Corinne Pondarré

2006

Regulation of interaction of the iron-responsive element binding protein with iron-responsive RNA elements

Molecular and cellular biology, 1989

Human iron regulatory protein 2 is easily cleaved in its specific domain: consequences for the haem binding properties of the protein

Jean-marc Moulis

Biochemical Journal, 2007

Reciprocal control of RNA-binding and aconitase activity in the regulation of the iron-responsive element binding protein: role of the iron-sulfur cluster

Proceedings of the National Academy of Sciences, 1992

Cooperation of Two MRNA-Binding Proteins Drives Metabolic Adaptation to Iron Deficiency

Sandra Vergara

Cell metabolism, 2008

Differences in the RNA binding sites of iron regulatory proteins and potential target diversity

James Basilion

Proceedings of the National Academy of Sciences, 1996

Iron regulatory protein 1 is not required for the modulation of ferritin and transferrin receptor expression by iron in a murine pro-B lymphocyte cell line

Kenneth Blemings

Proceedings of the National Academy of Sciences, 1997

Regulation of cellular iron metabolism

Identification of RNA-binding surfaces in iron regulatory protein-1

Rémy Moret

The EMBO Journal, 1999

The intracellular location of iron regulatory proteins is altered as a function of iron status in cell cultures and rat brain

DomingoJ Pinero

The Journal of …, 2001

An overview of molecular basis of iron metabolism regulation and the associated pathologies

Bruno Silva

Biochimica et biophysica acta, 2015

Subcellular localization of iron regulatory proteins to Golgi and ER membranes

Domingo Pinero

Journal of Cell Science, 2005

Iron-Dependent Degradation of Apo-IRP1 by the Ubiquitin-Proteasome Pathway

Molecular and Cellular Biology, 2007

Regulation of ferritin and heme oxygenase synthesis in rat fibroblasts by different forms of iron

Doris Garcia-Rivera

Proceedings of the …, 1991

Detection of intracellular iron by its regulatory effect

Cathy Savage-dunn

AJP: Cell Physiology, 2004

Cloning of the cDNA encoding an RNA regulatory protein--the human iron-responsive element-binding protein

Proceedings of the National Academy of Sciences, 1990