Negative selection of T cells causing lethal graft-versus-host disease across minor histocompatibility barriers. Role of the H-2 complex (original) (raw)

Analysis of histocompatibility requirements for proliferative and helper T cell activity. T cell populations depleted of alloreactive cells by negative selection

Polly Matzinger

Journal of Experimental Medicine, 1980

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Loss of graft-versus-host reactivity of mouse lymphocytes during serial passage through irradiated allogeneic hosts

Bengt Andersson

Cellular Immunology, 1973

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Selection of cytotoxic T-cell precursors specific for minor histocompatibility determinants. I. Negative selection across H-2 barriers induced with disrupted cells but not with glutaraldehyde- treated cells: evidence for antigen processing

J. Sprent

Journal of Experimental Medicine, 1980

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Division rate and phenotypic differences discriminate alloreactive and nonalloreactive T cells transferred in lethally irradiated mice

D. Klatzmann

Blood, 2001

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Antigen-specific T cell responses in human peripheral blood leucocyte (hu-PBL)–mouse chimera conditioned with radiation and an antibody directed against the mouse IL-2 receptor β-chain

Geert Leroux-Roels

Clinical and Experimental Immunology, 2000

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Different subsets of T cells in the adult mouse bone marrow and spleen induce or suppress acute graft-versus-host disease

Bari Nazario

The Journal of Immunology

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Synergy Among Lymphoid Cells Mediating the Graft-Versus-Host Response

Robert Tigelaar

Journal of Experimental Medicine, 1973

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Graft-versus-host mortality induced by noncytolytic CD4+ T cell clones specific for non-H-2 antigens

isabelle miconnet

The Journal of Immunology

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Most gamma delta T cells develop normally in the absence of MHC class II molecules

Paul Bleicher

Journal of Immunology, 1993

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Predominance of NK1.1TCR or DX5TCR T Cells in Mice Conditioned with Fractionated Lymphoid Irradiation Protects Against Graft-Versus-Host Disease: "Natural Suppressor" Cells1

Philip Huie

2000

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Prevention of Graft-Versus-Host Disease by Induction of Immune Tolerance With Ultraviolet B-Irradiated Leukocytes in H-2 Disparate Bone Marrow Donor

KJ Kao

Blood, 1999

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MHC-dependent survival of naïve T cells? A complicated answer to a simple question

Jeffrey Dorfman

Microbes and Infection, 2002

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Minimal conditioning required in a murine model of T cell depletion, thymic irradiation and high-dose bone marrow transplantation for the induction of mixed chimerism and tolerance

Boris Nikolic

Transplant International, 2002

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Acute lethal graft-versus-host reaction induced by major histocompatibility complex class II-reactive T helper cell clones

Fiorenza Falcioni

The Journal of experimental medicine, 1990

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The Response of T Cells to HISTOCOMPATIBILITY-2 Antigens: Dose-Response Kinetics

Stephen Liebhaber

Journal of Experimental Medicine, 1972

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Early treatment with CD4+CD25+ regulatory T cells provides prolonged suppressive effects which control evolving but not established graft-versus-host-disease

Christopher H Contag

Biology of Blood and Marrow Transplantation, 2006

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Induction of cutaneous graft-versus-host disease by local injection of unprimed T cells

Kazuhiro Kawai

Clinical & Experimental Immunology, 2008

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Effects of T cell depletion in radiation bone marrow chimeras. II. Requirement for allogeneic T cells in the reconstituting bone marrow inoculum for subsequent resistance to breaking of tolerance

Michael Sheard

Journal of Experimental Medicine, 1988

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MHC Class II Molecules Are Not Required for Survival of Newly Generated CD4+ T Cells, but Affect Their Long-Term Life Span

Hiroshi Arakawa

Immunity, 1996

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Enhanced and aberrant T cell trafficking following total body irradiation: a gateway to graft-versus-host disease?

fabrizio vianello

British Journal of Haematology, 2013

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Generation of primary antigen-specific human cytotoxic T lymphocytes in human/mouse radiation chimera

Harry Segall

Blood, 1996

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Immunogenetics of graft-versus-host reactions to minor histocompatibility antigens

J. Sprent

Immunology Today, 1981

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Lymphohematopoietic graft-vs.-host reactions can be induced without graft-vs.-host disease in murine mixed chimeras established with a cyclophosphamide-based nonmyeloablative conditioning regimen

Megan Sykes

Biology of Blood and Marrow Transplantation, 1999

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Low-Dose Total-Body Irradiation and Fludarabine Followed by Hematopoietic Cell Transplantation From HLA-Identical Sibling Donors Do Not Induce Complete T-Cell Donor …

Carmen martínez

Experimental …, 2003

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Role of Antigen-Presenting Cells in the Cytotoxic T-Cell Response to Minor Histocompatibility Antigens (MIHA)

Zeinab Mohamed

Scandinavian Journal of Immunology, 1987

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Differential effectiveness of anti-CD8 treatment on ongoing graft-versus-host reactions in mice

huub savelkoul

Transplant Immunology, 1996

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Significant MLR but not CTL responses against recipient antigens generated in T cells from bone marrow chimeras recovered from acute GVHD

Kazuya Iwabuchi

Bone Marrow Transplantation, 2000

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Capacity of genetically different T lymphocytes to induce lethal graft-versus-host disease correlates with their capacity to generate suppression but not with their capacity to generate anti-F1 killer cells. A non-H-2 locus determines the inability to induce lethal graft-versus-host disease

Ernst Gleichmann

The Journal of experimental medicine, 1981

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A novel approach for prevention of lethal GVHD by selective elimination of alloreactive donor lymphocytes prior to stem cell transplantation

Soumya Panigrahi

Experimental Hematology, 2004

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Allosuppression of B cellsin vitro by graft-vs.-host reaction-derived T cells is caused by cytotoxic T lymphocytes

Cornelis Melief

European Journal of Immunology, 1989

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Donor-specific tolerance in a murine model: the result of extra-thymic T cell deletion?

Jose Vingerhoed

Transplant Immunology, 2003

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Clonal deletion of self-reactive T cells in irradiation bone marrow chimeras and neonatally tolerant mice. Evidence for intercellular transfer of Mlsa

Reto Schneider

Journal of Experimental Medicine, 1989

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Positive selection of T-lymphocytes induced by intrathymic injection of a thymic epithelial cell line

Barbara B. Knowles

Nature, 1992

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The use of parabiosis for investigating the mechanism of transplantation tolerance in bone marrow chimeras induced by total lymphoid irradiation

Ahmed Eid

Transplant International, 1990

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Synergy During in Vitro Cytotoxic Allograft Responses: I. Evidence for Cell Interaction Between Thymocytes and Peripheral T Cells

Hermann Wagner

Journal of Experimental Medicine, 1973

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