original ) (raw )Novel Bacterial Topoisomerase Inhibitors with Potent Broad-Spectrum Activity against Drug-Resistant Bacteria
Mark Craighead
Antimicrobial agents and chemotherapy, 2017
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Oxabicyclooctane-Linked Novel Bacterial Topoisomerase Inhibitors as Broad Spectrum Antibacterial Agents
Peter Meinke
ACS Medicinal Chemistry Letters, 2014
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The Structural Features of Novel Bacterial Topoisomerase Inhibitors That Define Their Activity on Topoisomerase IV
Martina Hrast
Journal of Medicinal Chemistry, 2022
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NBTI 5463 Is a Novel Bacterial Type II Topoisomerase Inhibitor with Activity against Gram-Negative Bacteria and In Vivo Efficacy
Asha Nayar , Thomas Dougherty
Antimicrobial Agents and Chemotherapy, 2014
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Type IIA topoisomerase inhibition by a new class of antibacterial agents
Alexandre Wohlkonig
Nature, 2010
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Novel Tetrahydropyran-Based Bacterial Topoisomerase Inhibitors with Potent Anti-Gram Positive Activity and Improved Safety Profile
Michel Enderlin-Paput , Eric Ertel
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Discovery and Optimization of Indolyl-Containing 4-Hydroxy-2-Pyridone Type II DNA Topoisomerase Inhibitors Active against Multi-Drug Resistant Gram-Negative Bacteria
Marla Weetall
Journal of medicinal chemistry, 2018
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Recent advancements in the medicinal chemistry of bacterial type II topoisomerase inhibitors
Shalini jaswal
Bioorganic Chemistry, 2020
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Left hand side exploration of novel bacterial topoisomerase inhibitors to improve selectivity against hERG binding
Gajanan Shanbhag , Jayashree Puttur , Anandkumar Raichurkar
ACS Medicinal Chemistry Letters, 2015
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De Novo Design of Type II Topoisomerase Inhibitors as Potential Antimicrobial Agents Targeting a Novel Binding Region
Thomas Germe
2021
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Cyclohexyl amide-based novel bacterial topoisomerase inhibitors with prospective GyrA-binding fragments
Martina Hrast
Future Medicinal Chemistry, 2019
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Synthesis and Characterization of Tetrahydropyran-Based Bacterial Topoisomerase Inhibitors with Antibacterial Activity against Gram-Negative Bacteria
Michel Enderlin-Paput , Eric Ertel
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Two Decades of Successful SAR-Grounded Stories of the Novel Bacterial Topoisomerase Inhibitors (NBTIs)
Marko Anderluh
Journal of Medicinal Chemistry
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Exploring Left-Hand-Side substitutions in the benzoxazinone series of 4-amino-piperidine bacterial type IIa topoisomerase inhibitors
Stewart Fisher
Bioorganic & Medicinal Chemistry Letters, 2011
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In Vitro Characterization of the Antibacterial Spectrum of Novel Bacterial Type II Topoisomerase Inhibitors of the Aminobenzimidazole Class
Mike Hamblin
Antimicrobial Agents and Chemotherapy, 2006
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Discovery and Optimization of DNA Gyrase and Topoisomerase IV Inhibitors with Potent Activity against Fluoroquinolone-Resistant Gram-Positive Bacteria
bhavesh dhumale
Journal of Medicinal Chemistry, 2021
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Target-Based Resistance in Pseudomonas aeruginosa and Escherichia coli to NBTI 5463, a Novel Bacterial Type II Topoisomerase Inhibitor
Adam Shapiro
Antimicrobial Agents and Chemotherapy, 2014
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In Vitro and In Vivo Activities of PD 0305970 and PD 0326448, New Bacterial Gyrase/Topoisomerase Inhibitors with Potent Antibacterial Activities versus Multidrug-Resistant Gram-Positive and Fastidious Organism Groups
Edmund Ellsworth
Antimicrobial Agents and Chemotherapy, 2007
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Novel N-Linked Aminopiperidine Inhibitors of Bacterial Topoisomerase Type II with Reduced pK a : Antibacterial Agents with an Improved Safety Profile
Patrick Brassil
Journal of Medicinal Chemistry, 2012
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Topoisomerase Inhibitors Addressing Fluoroquinolone Resistance in Gram-Negative Bacteria
krunal prajapati
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Structure activity relationship of C-2 ether substituted 1,5-naphthyridine analogs of oxabicyclooctane-linked novel bacterial topoisomerase inhibitors as broad-spectrum antibacterial agents (Part-5)
Yasumichi Fukuda
Bioorganic & Medicinal Chemistry Letters, 2015
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Structure–activity relationships of 3-aminoquinazolinediones, a new class of bacterial type-2 topoisomerase (DNA gyrase and topo IV) inhibitors
Rajeshwar Singh
Bioorganic & Medicinal Chemistry Letters, 2007
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