Inhibition of lysosomal phospholipase A and phospholipase C by chloroquine and 4,4'-bis(diethylaminoethoxy) alpha, beta-diethyldiphenylethane (original ) (raw )Studies on the mechanism of drug-induced lipidosis
Karl Y Hostetler
Biochemical Pharmacology, 1981
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Chloroquine treatment does not cause phospholipid storage by depleting rat liver lysosomes of acid phospholipase a
Karl Y Hostetler
Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, 1984
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Studies on drug-induced lipidosis: subcellular localization of phospholipid and cholesterol in the liver of rats treated with chloroquine or 4,4'-bis (diethylaminoethoxy)alpha, beta-diethyldiphenylethane
Karl Y Hostetler
Journal of lipid research, 1980
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Drug-induced Phospholipidosis -Pathological Aspects and Its Prediction
Ryo Fukuda
Journal of Toxicologic Pathology, 2008
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Comparison of the Diagnostic Accuracy of Di-22:6-Bis(monoacylglycerol)Phosphate and Other Urinary Phospholipids for Drug-Induced Phospholipidosis or Tissue Injury in the Rat
Jun Zhang
International Journal of Toxicology, 2012
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Different Sensitivity of Macrophages to Phospholipidosis Induction by Amphiphilic Cationic Drugs
Eleonore Fröhlich
International Journal of Molecular Sciences, 2020
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Pharmacological properties of phospholipid liposomes
Gino Toffano
Pharmacological research communications, 1980
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Interactions of primaquine and chloroquine with PEGylated phosphatidylcholine liposomes
Noorma Rosita
Scientific Reports, 2021
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Increased levels of urinary phenylacetylglycine associated with mitochondrial toxicity in a model of drug-induced phospholipidosis
Hans Senn
Therapeutic advances in drug safety, 2013
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Lysosomal lipolytic enzymes, lipid peroxidation, and injury
William Weglicki
Molecular and Cellular Biochemistry, 1988
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Modulation of the in vitro activity of lysosomal phospholipase A1 by membrane lipids
Marie-Paule Mingeot
Chemistry and physics …, 2005
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Properties of phospholipase C isolated from rat liver lysosomes
Karl Y Hostetler
The Journal of biological chemistry, 1980
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Inhibition of kidney lysosomal phospholipases A and C by aminoglycoside antibiotics: possible mechanism of aminoglycoside toxicity
Karl Y Hostetler
Proceedings of the National Academy of Sciences, 1982
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Effect of local anesthetics on phospholipases from mitochondria and lysosomes. Probe into the role of the calcium ion in phospholipid hydrolysis
Patricia Sisson
Biochemistry, 1972
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A lipidomic cell-based assay for studying drug-induced phospholipidosis and steatosis
Agustín Lahoz
ELECTROPHORESIS, 2017
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In vitro inhibition of lysosomal phospholipase A1 of rat lung by amiodarone and desethylamiodarone
Karl Y Hostetler
Biochimica et biophysica acta, 1988
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The Contribution of Lysosomal Trapping in the Uptake of Desipramine and Chloroquine by Different Tissues
W. Daniel
Pharmacology & Toxicology, 1995
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Drug-induced surface membrane phospholipid composition in murine fibroblasts
Daniel Feller
Biochimica et Biophysica Acta (BBA) - Biomembranes, 1981
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Lysosomotropic cationic drugs induce cytostatic and cytotoxic effects: Role of liposolubility and autophagic flux and antagonism by cholesterol ablation
Alexandre Parks
Toxicology and Applied Pharmacology, 2016
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Cellular Responses Associated with Dibucaine-Induced Phospholipidosis
José Manuel Pérez Martín
Chemical Research in Toxicology, 2011
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Modifications of phospholipid metabolism induced by chlorpromazine, desmethylimipramine and propranolol in C6 glioma cells
Ubaldo Leli
Biochemical Pharmacology, 1987
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Lipid peroxidation and phospholipase A2 activity in liposomes composed of unsaturated phospholipids: a structural basis for enzyme activation
Mary Lou Wratten
Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, 1988
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Pharmacokinetic characterization of phosphatidylserine liposomes in the rat
Giampietro Viola
British Journal of Pharmacology, 1991
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Mechanism of modification of rat brain lysophospholipase A activity by cationic amphiphilic drugs
Ubaldo Leli
Biochimica et biophysica acta, 1987
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Selective Inhibition of Phosphatidylinositol Phospholipase C by Cytotoxic Ether Lipid Analogues
Catherine Gratas
Cancer Research
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The biologically active phospholipid, lysophosphatidic acid, induces phosphatidylcholine breakdown in fibroblasts via activation of phospholipase D. Comparison with the response to endothelin
John de Widt
The Biochemical journal, 1992
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Lysosomal Sequestration (Trapping) of Lipophilic Amine (Cationic Amphiphilic) Drugs in Immortalized Human Hepatocytes (Fa2N-4 Cells)
Faraz Kazmi
Drug Metabolism and Disposition, 2013
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Disturbance of lysosomal glycogen metabolism by liposomal anti-alpha-glucosidase and some anti-inflammatory drugs
Don Otter
Biochemical Journal, 1983
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Is Lysosomal Enzymes Changes Important In the Pathogenesis of Liver And Kidney Injury Induced By Short and Long Term Administration of Some NSAID ' Drugs in Rats ?
kamal eldeib
2012
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Cationic amphiphilic drugs induce elevation in lysoglycerophospholipid levels and cell death in leukemia cells
Inger Nielsen
Metabolomics, 2020
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Detection of Phospholipidosis Induction: A Cell-Based Assay in High-Throughput and High-Content Format
David Gerhold
2014
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