Cerebral and Systemic Hemodynamic Effects of Intravenous Bolus Administration of Propofol in Neonates (original) (raw)

suggesting a better balance between oxygen delivery and demand. PNA ^ 10 days, comedication and absence of cardiopathy were associated with more subtle decreases in cerebral oxygenation and faster recovery. Conclusions: Propofol-induced decrease in HR, SaO 2 and cerebral oxygenation is short lasting while a decrease in MABP is observed up to 60 min. The variability in the effects of propofol is influenced by PNA, comedication or cardiopathy. Near-infrared spectroscopy can be used to assess hemodynamic effects of hypnotics on the cerebral oxygenation.