Prehospital cardiac arrest: a marker for higher mortality in patients with acute myocardial infarction and moderately reduced left ventricular function: results from the MITRA plus registry (original) (raw)

According to the current guidelines for acute myocardial infarction, ventricular fibrillation during the acute phase of myocardial infarction is not an indication for specific treatment like ICD implantation. This study aimed to evaluate the prognostic significance of prehospital cardiac arrest in patients with moderately reduced left ventricular function (LVEF 30-55%) who survived acute ST-elevation myocardial infarction (STEMI). Analysis of the MITRA plus registry revealed that out of 7111 patients with acute STEMI and LVEF >30%, those who experienced prehospital cardiac arrest had a significantly higher long-term mortality (13.6%) compared to those without cardiac arrest (8.7%), despite being younger and having fewer risk factors. This indicates that prehospital cardiac arrest is an independent risk factor for higher mortality in this patient population. Further investigation is warranted to understand the impact of ICD implantation in these patients.