NF-κB activation fails to protect cells to TNFα-induced apoptosis in the absence of Bcl-xL, but not Mcl-1, Bcl-2 or Bcl-w (original) (raw)

Bcl-2 Suppresses Apoptosis Resulting from Disruption of the NF-κB Survival Pathway☆

John Herrmann

Experimental Cell Research, 1997

View PDFchevron_right

Bcl-2 protects from oxidative damage and apoptotic cell death without interfering with activation of NF-κB by TNF

C. victor Jongeneel

FEBS Letters, 1994

View PDFchevron_right

BCL-XL regulates TNF-α-mediated cell death independently of NF-κB, FLIP and IAPs

Stephany Segura

Cell Research, 2008

View PDFchevron_right

The pro- or anti-apoptotic function of NF-κB is determined by the nature of the apoptotic stimulus

Barbara Kaltschmidt

European Journal of Biochemistry, 2000

View PDFchevron_right

The biological and clinical impact of inhibition of NF-κB-initiated apoptosis in diffuse large B cell lymphoma (DLBCL)

Jehad Abubaker

The Journal of Pathology, 2011

View PDFchevron_right

Overexpression of Bcl-xs Sensitizes MCF-7 Cells to Chemotherapy-induced Apoptosis1

Venil N Sumantran

View PDFchevron_right

Cytokine-induced β-cell apoptosis is NO-dependent, mitochondria-mediated and inhibited by BCL-X L

Afshin Samali, Thomas Ritter

Journal of Cellular and Molecular Medicine, 2008

View PDFchevron_right

Diverse TNFα-induced death pathways are enhanced by inhibition of NF-κB

Elena Efimova

International Journal of Oncology, 2007

View PDFchevron_right

Constitutive Activation of NF-κB Causes Resistance to Apoptosis in Human Cutaneous T Cell Lymphoma HuT-78 Cells

Dhananjay giri

Journal of Biological Chemistry, 1998

View PDFchevron_right

Bcl2 and BclXL serve an anti-inflammatory function in endothelial cells through inhibition of NF-κB

Guadalupe Beth

Journal of Clinical Investigation, 1999

View PDFchevron_right

Bcl-xL Functions Downstream of Caspase-8 to Inhibit Fas- and Tumor Necrosis Factor Receptor 1-induced Apoptosis of MCF7 Breast Carcinoma Cells

Joseph Wu

Journal of Biological Chemistry, 1998

View PDFchevron_right

Disruption of NF-κB Signaling Reveals a Novel Role for NF-κB in the Regulation of TNF-Related Apoptosis-Inducing Ligand Expression

Tudor Baetu

Journal of Immunology, 2001

View PDFchevron_right

Bcl-xL/Bax ratio is altered by IFNγ in TNFα- but not in TRAIL-induced apoptosis in colon cancer cell line

Jacques Marvaldi

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 2005

View PDFchevron_right

Pro-apoptotic role of NF-κB: Implications for cancer therapy

Senthil Radhakrishnan

Biochimica et Biophysica Acta (BBA) - Reviews on Cancer, 2006

View PDFchevron_right

Transcriptional regulation of TNF family receptors and Bcl-2 family by chemotherapeutic agents in murine CT26 cells

Jae-Kyun Ko

Journal of Cellular Biochemistry, 2004

View PDFchevron_right

Dying for NF-κB? Control of cell death by transcriptional regulation of the apoptotic machinery

Ezra Burstein

Current Opinion in Cell Biology, 2003

View PDFchevron_right

Ectopic Expression of Protein-tyrosine Kinase Bcr-Abl Suppresses Tumor Necrosis Factor (TNF)-induced NF-kappa B Activation and Ikappa Balpha Phosphorylation. RELATIONSHIP WITH DOWN-REGULATION OF TNF RECEPTORS

Asok Mukhopadhyay

Journal of Biological Chemistry, 2002

View PDFchevron_right

Control of B Lymphocyte Apoptosis by the Transcription Factor NF-κB

Ranjan Sen

Immunity, 2006

View PDFchevron_right

Expression of BCL-2 protein enhances the survival of mouse fibrosarcoid cells in tumor necrosis factor-mediated cytotoxicity

Giuseppe Bertoni

Cancer research, 1993

View PDFchevron_right

In vivo suppression of Bcl-XL expression facilitates chemotherapy-induced leukaemia cell death in a SCID/NOD-Hu model

Finbarr Cotter

British Journal of Haematology, 2001

View PDFchevron_right

Bcl-2 transgene expression fails to prevent fatal hepatocyte apoptosis induced by endogenous TNFα in mice lacking RelA

Aliki Christou

Cell Death and Differentiation, 2006

View PDFchevron_right

Constitutive nuclear factor-kappa B activity preserves homeostasis of quiescent mature lymphocytes and granulocytes by controlling the expression of distinct Bcl-2 family proteins

Marie-paule Merville

Blood, 2002

View PDFchevron_right

Bcl-3 promotes TNF-induced hepatocyte apoptosis by regulating the deubiquitination of RIP1

Yufang Shi

Cell Death & Differentiation, 2021

View PDFchevron_right

TNF-Induced Signaling in Apoptosis

PRAMOD RATH

1999

View PDFchevron_right

Disruption of NF-{kappa} B signaling reveals a novel role for NF-{kappa} B in the regulation of TNF-related apoptosis-inducing ligand expression

Tudor Baetu

The Journal of …, 2001

View PDFchevron_right

Inhibition of NF-kappaB/Rel induces apoptosis of murine B cells

Marcello Arsura

The EMBO Journal, 1996

View PDFchevron_right

The interplay between the Bcl-2 family and death receptor-mediated apoptosis

Martin Sprick

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 2004

View PDFchevron_right

Down-regulation of apoptosis-related bcl-2 but not bcl-xL or bax proteins in multidrug-resistant MCF-7/Adr human breast cancer cells

B. Ogretmen

International Journal of Cancer, 1996

View PDFchevron_right

MAP kinase-dependent, NF-κB-independent regulation of inhibitor of apoptosis protein genes by TNF-α

Tsuneo Konta

Journal of Cellular Physiology, 2007

View PDFchevron_right

Crosstalk between NF-κB-activating and apoptosis-inducing proteins of the TNF-receptor complex

karen heyninck

Molecular Cell Biology Research Communications, 2001

View PDFchevron_right

Apoptosis induces Bcl-XS and cleaved Bcl-XL in chronic lymphocytic leukaemia

Simon Wagner

Biochemical and Biophysical Research Communications, 2011

View PDFchevron_right

Selective Induction of Apoptosis by PBOX-6 in Leukemia Cells occurs via the JNK Dependent Phosphorylation and Inactivation of Bcl2 and BclXL

Daniela Zisterer

2000

View PDFchevron_right

Suppression of Tumor Necrosis Factor-Induced Cell Death by Inhibitor of Apoptosis c-IAP2 is under NF-kappa B Control

Lily Liu

Proceedings of The National Academy of Sciences, 1997

View PDFchevron_right