Human blood lymphocyte subsets separated on the basis of nylon adherence, SRBC and EA rosetting: Natural cytotoxicity and characterization with monoclonal reagents (original) (raw)

Abstract

sparkles

AI

Lymphocyte subsets were separated using nylon-wool adherence and characterized by monoclonal antibodies. Analysis revealed a heterogeneous population, with varying reactivity among subsets towards K562 and Daudi targets, influenced by IFN activation. The study highlights phenotypic diversity in blood lymphocytes, providing insights into their functional characteristics.

Loading...

Loading Preview

Sorry, preview is currently unavailable. You can download the paper by clicking the button above.

References (26)

  1. Bakacs, T., Klein, E., Steinitz, M., and Gergely, P., Huematologia 12( l-4), 113, 1978-79.
  2. Hersey, P., Edwards, A., Edwards, J., Adams, E., Milton, G. W., and Nelson, D. S., Inr. J. Cancer 16, 173, 1975.
  3. West, H. W., Cannon, G. B., Kay, H. D., Bonnard, G. H., and Herbermann, R. B., J. Zmmunol. 118, 355, 1977.
  4. Masucci, M. G., Masucci, G., Klein, E., and Berthold, W., Proc. Nut. Acud. Sci. USA 77, 3620, 1980.
  5. Poros, A., and Klein, E., Cell. Immunol. 41, 240, 1978.
  6. Bakacs, T., Gergely, P., and Klein, E., Cell. Immunol. 32, 317, 1977.
  7. Masucci, G., Masucci, M. G., and Klein, E. Cell Immunol. 69, 21-33.
  8. Lundgren, G., Zukoski, Ch. F., and Moller, G., Clin. Exp. Immunol. 3, 817, 1968.
  9. Julius, M. H., Simpson, E., and Herzenberg, L. A., Eur. J. Immunol. 3, 645, 1973.
  10. Reinherz, E. L., Kung, P. C., Goldstein, G., and Schlossman, S. F., Proc. Nut. Acud. Sci. USA 76, 4061, 1979. Il. Reinherz, E. L., Kung, P. C., Goldstein, G., and Schlossman, S. F., J. Zmmunol. 123, 1312, 1979.
  11. Kung, P. C., Goldstein, G., Reinherz, E. L., and Schlossman, S. F., Science 206, 347, 1979.
  12. Reinherz, E. L., Kung, P. C., Goldstein, G., and Schlossman, S. F., J. Zmmunol. 123, 2894, 1979.
  13. Reinherz, E. L., Kung, P. C., Pesando, J. M., Ritz, J., Goldstein, G., and Schlossman, S. F., J. Exp. Med. 150, 1472, 1979.
  14. Breard, J., Reinherz, E. L., Kung, P. C., Goldstein, G., and Schlossman, S. F., J. Immunol. 124, 1943, 1980.
  15. Reinherz, E. L., Kung, P. C., Breard, J. M., Goldstein, G., and Schlossman, S. F., J. Immunol. 124, 1883, 1980.
  16. Timonen, T., Saksela, E., Ranki, A., and Hlyry, P., Cell. Immunol. 48, 133, 1979.
  17. Saksela, E., Timonen, T., Ranki, A., and Hayry, P., Zmmunol. Rev. 44, 71, 1979.
  18. Timonen, T., Ortaldo, J., and Herberman, R., J. Exp. Med. 153, 569, 1981.
  19. Grossi, C. E., Webb, S. R., Zicca, A., Lydyard, P., Moretta, L., Mingari, M. C., and Cooper, M. D., J. Exp. Med. 147, 1405, 1978.
  20. Reinherz, E. L., Moretta, L., Roper, M., Breard, J. M., Mingari, M. C., Cooper, M. D., and Schlossman, S. F., J. Exp. Med. 151, 969, 1980.
  21. Kay, H. D., and Horwitz, D. A., J. Clin. Invest. 66, 847, 1980.
  22. Zarling, J. M., and Kung, P. C., Nature (London) 288, 394, 1980.
  23. Zarling, J. M., Clouse, K. A., Biddison, W. E., and Kung, P. C., J. Immunol., 127, 2575, 1981.
  24. Fast, L. D., Hansen, J. A., and Newman, W., J. Immunol. 127, 448, 1981.
  25. Poros, A., Ahrlund-Richter, L., Klein, E., Hammarstrom, S., and Koide, N., submitted for publi- cation.
  26. Perussia, B., Fanning, V., and Trinchieri, G., in press.