A 24x16 CMOS-Based Chronocoulometric DNA Microarray (original) (raw)

CMOS-based DNA microarrays utilizing electrochemical detection principles have attracted a huge amount of interest for applications in biotechnological research and medical diagnostics, since they avoid expensive and relatively bulky optical setups used in most state-of the art DNA microarray systems . Moreover, they provide synergy to and easy adaptation of techniques to electrically control immobilization of DNA probe molecules, in-situ synthesis of DNA probe molecules, or stringency during hybridization .