Crystallins and their synthesis in human lens epithelial cells in tissue culture (original) (raw)

This research investigates the establishment and characterization of human lens epithelial cells (HLECs) in tissue culture, highlighting their significance in studying cataract etiology and cell differentiation. It identifies the synthesis of alpha- and beta-crystallins in HLECs, noting the unexpected presence of gamma-crystallin despite the absence of lentoid body formation. The findings suggest that culture conditions and harvesting times significantly impact cellular differentiation markers and urge further exploration of optimized culture techniques.