Antihypertensive Prescribing Practices: Impact of the Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (original) (raw)

2006, The Journal of Clinical Hypertension

This national study examines the impact of the Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT) on the prescribing of thiazide-type diuretics and other antihypertensive medications for patients with newly diagnosed hypertension. A cross-sectional analysis was conducted using data from a national network of electronic health records for 2 groups with newly diagnosed hypertension and started on antihypertensive medications: one a year before and the other a year after the publication of ALLHAT. The percentage of new hypertensives started on thiazides increased from 29% pre-ALLHAT to 39% post-ALLHAT. An increase was also seen for angiotensin receptor blockers, while prescribing for angiotensinconverting enzyme inhibitors, calcium channel blockers, and β-blockers declined. There was no significant change in prescriptions for α-blockers. ing practices. (J Clin Hypertens. 2006;8:860-864) al. Age-specific relevance of usual blood pressure to vascular mortality: a meta-analysis of individual data for one million adults in 61 prospective studies. Lancet. 2002;360:1903-1913 Cutler JA, MacMahon SW, Furberg CD. Controlled clinical trials of drug treatment for hypertension. A review.

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