Selecting a more realistic uncertainty factor: Reducing compounding effects of multiple uncertainties (original) (raw)

Human and Ecological Risk Assessment, 1995

Abstract

Available toxicology datasets provide a unique opportunity to validate some of the currently used Uncertainty Factors in the development of acceptable exposure levels for noncancer effects. Toxicity studies from two separate sources, the FAO/WHO database on pesticides (1978–1987) and the Monsanto database (through 1988) were chosen to evaluate three of the five currently used Uncertainty Factors. Interspecies differences in NOELs

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