A modular computer-controlled fermentation pilot-plant (original) (raw)
1991, Process Biochemistry
A computer-controlled pilot-plant for the fermentation of both microorganisms and animal cells was designed and set up jbr the scaleup of processes and the production of sample material for clinical trials. The modular design of the fermentation units allows ji)r the adaption to the specljic requirements of production organisms. Extensive documentation of batches, as required by regulatory authorities are achieved by the direct digital control concept with an industriul process control computer system. The pilot-plant hardware is presented and the development of the process control software described. Corresponding author : Dr. 0. Doblhoff-Dier. Telephone : (043-l) 3692924-402; Fax : (043-I) 3692924-400. l Fermentation of both microorganisms and animal or insect cells. 201 Process Biochemistry 0032-9592/91 /S3.50 Q 1991 Elsevier Science Publishers Ltd, England.
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