Wilms Tumor: Prognosis Using Microvessel Density (original) (raw)

Methods of Cancer Diagnosis, Therapy, and Prognosis, 2009

Abstract

Wilms tumor (WT), the most common malignant neoplasm of the kidney in infants and children, is a triphasic tumor that mimics various stages of nephrogenesis, composed of epithelial, blastemal and stromal cells. More than 90% of the cases occur in children less than 6-years of age, mostly between 2 and 5 years. WT has overall survival rates exceeding 90% by the improvement of surgical and anesthetic procedures, and the combination of chemotherapy and radiotherapy (D’Angio et al. 1989; Argani and Beck­with 2004).

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