Vitamin D level among patients with sickle cell anemia and its influence on bone mass (original) (raw)

Background: Both SCD and Vit. D deficiency may cause joint pain. So, Vit. D may have a contributory role in severity of SCD presentation. This study was performed to assess burden of Vitamin D levels and association of vitamin D deficiency with severity of SCD in a tertiary care centre in India.Methods: This was a cross-sectional study, performed for one and half year. All SCD patients >18 years of age were included. Data was analysed to assess the burden of Vitamin D deficiency and to find out any correlation of S. vitamin D level with anemia, jaundice and number of episodes of hospital admissions in patients of SCD.Results: Total 50 patients were included. Multiple joint pain and easy fatigability were the most common symptoms. Most of them had history of jaundice and anaemia in the past, 84% had Vitamin D deficiency. There was significant difference in values of serum total bilirubin, blood urea, SGPT, SGOT, HbF, HbA2 and haemoglobin between the patients with Vitamin D3<30...