Identification of arginine as a precursor of endothelium-derived relaxing factor (original) (raw)
L-arginine is the physiological precursor for the formation of nitric oxide in endothelium-dependent relaxation
Daryl Rees
Biochemical and Biophysical Research Communications, 1988
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A specific inhibitor of nitric oxide formation from l-arginine attenuates endothelium-dependent relaxation
Daryl Rees
British Journal of Pharmacology, 1989
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Nitric oxide and another potent vasodilator are formed from NG-hydroxy-L-arginine by cultured endothelial cells
William Sessa
Proceedings of the National Academy of Sciences, 1991
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Activated murine macrophages secrete a metabolite of arginine with the bioactivity of endothelium-derived relaxing factor and the chemical reactivity of nitric oxide
Dennis Stuehr
Journal of Experimental Medicine, 1989
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NG-monomethyl L-arginine inhibits endothelium-derived relaxing factor-stimulated cyclic GMP accumulation in cocultures of endothelial and vascular smooth muscle cells by an action specific to the endothelial cell
Joel Linden
Circulation Research, 1990
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P094. Receptor-mediated activation of nitric oxide synthesis by arginine in endothelial cells
Bruce Ferguson
Nitric Oxide, 2006
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Effect of NG-monomethyl L-arginine on endothelium-dependent relaxation in arterioles of one-kidney, one clip hypertensive rats
R. Woolfson
Hypertension, 1991
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The metabolism of L-arginine and its significance for the biosynthesis of endothelium-derived relaxing factor: L-glutamine inhibits the generation of L-arginine by cultured endothelial cells
William Sessa
1990
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Long-term oral administration of L-arginine reduces intimal thickening and enhances neoendothelium-dependent acetylcholine-induced relaxation after arterial injury
Nicolas Wernert
Circulation, 1994
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Interactions between L-arginine and L-glutamine change endothelial NO production. An effect independent of NO synthase substrate availability
William Mitch
Journal of Clinical Investigation, 1995
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INHIBITION OF ENDOTHELIAL NITRIC OXIDE BIOSYNTHESIS BY N-NITRO-l-ARGININE
Gregory Dusting
Clinical and Experimental Pharmacology and Physiology, 1990
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Impairment of pulmonary-artery endothelium-dependent relaxation in chronic obstructive lung disease is not due to dysfunction of endothelial cell membrane receptors nor to l-arginine deficiency
George Cremona
British Journal of Pharmacology, 1993
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Endothelium-dependent relaxation resistant to N/ω-nitro-L-arginine in the rat hepatic artery and aorta
Peter Zygmunt
Acta Physiologica Scandinavica, 1994
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L-Arginine does not improve endothelium-dependent relaxation inin vitro Watanabe rabbit thoracic aorta
Gjumrakch Aliev, Guglielmina Froldi
Amino Acids, 1993
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Critical dependence of the NO-mediated component of cyclic AMP-induced vasorelaxation on extracellular L-arginine in pulmonary arteries of the rat
David Hucks
British Journal of Pharmacology, 2000
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Nitric oxide is the mediator of both endothelium-dependent relaxation and hyperpolarization of the rabbit carotid artery
T. Malinski
Proceedings of the …, 1997
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Receptor-Mediated Activation of Nitric Oxide Synthesis by Arginine In Endothelial Cells
Mahesh Joshi
Proceedings of the …, 2007
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The role of nω-nitro-L-arginine in modulation of pulmonary vascular tone in the maturing newborn pig
Patrick Domkowski
The Journal of Thoracic and Cardiovascular Surgery, 1995
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Impairment of Smooth Muscle Function of Rat Thoracic Aorta In An Endothelium-Independent Manner by Long-Term Administration of NG-Nitro-L-Arginine Methyl Ester
Cindy Ortiz
Fundamental & …, 2004
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Modulation of the L-arginine/nitric oxide signalling pathway in vascular endothelial cells
Giovanni Mann
Biochemical Society Symposium, 2004
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Release of nitric oxide from human vascular smooth muscle cells
Ivo Gut
Biochemical and Biophysical Research Communications, 1991
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-adrenergic relaxation in pulmonary arteries: preservation of the endothelial nitric oxide-dependent 2 component in pulmonary hypertension
Lionel Leroux
Cardiovascular Research, 2007
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l-NG-monomethyl arginine and l-NG-nitro arginine inhibit non-adrenergic, non-cholinergic relaxation of the mouse anococcygeus muscle
Adrian Hobbs
British Journal of Pharmacology, 1990
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Relaxin Activates the L-Arginine Nitric Oxide Pathway in Vascular Smooth Muscle Cells in Culture
P. Failli
Hypertension, 1998
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Endothelium-Derived Relaxing Factor: Presence in Pulmonary and Systemic Arteries of the Newborn Guinea Pig
Alaa Eldemerdash
Pediatric Research, 1990
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NG-methyl-L-arginine inhibits tumor necrosis factor-induced hypotension: implications for the involvement of nitric oxide
Owen Griffith
Proceedings of the National Academy of Sciences, 1990
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Regulation of L-arginine transport and nitric oxide release in superfused porcine aortic endothelial cells
Richard Bogle
The Journal of …, 1996
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Regional differences in endothelium-dependent relaxation in the rat: contribution of nitric oxide and nitric oxide-independent mechanisms
Peter Zygmunt
Acta Physiologica Scandinavica, 1995
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Activated macrophages depress the contractility of rabbit carotids via an L-arginine/nitric oxide-dependent effector mechanism. Connection with amplified cytokine release
Alain Tedgui
Journal of Clinical Investigation, 1992
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Bradykinin and ATP stimulate L-arginine uptake and nitric oxide release in vascular endothelial cells
Richard Bogle
Biochemical and …, 1991
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