Structural, functional, and bioinformatics studies reveal a new snake venom homologue phospholipase A 2 class (original) (raw)

Profile image of Juliana dos SantosJuliana dos Santos

2010, Proteins: Structure, Function, and Bioinformatics

Structural and functional studies with mytoxin II from Bothrops moojeni reveal remarkable similarities and differences compared to other catalytically inactive phospholipases A2-like

Juliana dos Santos

Toxicon, 2013

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Structural and Functional Properties of BaTX, a New Lys49 Phospholipase A2 Homologue Isolated From the Venom of the Snake Bothrops Alternatus

Bruno Lomonte

… et Biophysica Acta (BBA …, 2007

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Comparison between apo and complexed structures of bothropstoxin-I reveals the role of Lys122 and Ca 2+-binding loop region for the catalytically inactive Lys49PLA 2s

Daniela Salvador

Journal of Structural Biology, 2010

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Comparative structural studies on Lys49-phospholipases A 2 from Bothrops genus reveal their myotoxic site

Juliana Santos

Journal of Structural Biology, 2009

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Preliminary X-ray crystallographic studies of BthTX-II, a myotoxic Asp49-phospholipase A 2 with low catalytic activity from Bothrops jararacussu venom

Daniela Salvador

Acta Crystallographica Section F-structural Biology and Crystallization Communications, 2006

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Structural and Phylogenetic Studies with MjTX-I Reveal a Multi-Oligomeric Toxin – a Novel Feature in Lys49-PLA2s Protein Class

Angelo Magro

PLoS ONE, 2013

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Crystal structure of a novel myotoxic Arg49 phospholipase A< sub> 2 homolog (zhaoermiatoxin) from< i> Zhaoermia mangshanensis snake venom: Insights into Arg49 coordination and the role of Lys122 in the polarization of the C-terminus

Mario Murakami

2008

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The crystal structure of a Lysine 49 Phospholipase A2 from the venom of the Cottonmouth Snake at 2.0-Å resolution

Barry Finzel

Journal of Biological Chemistry

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Structural, enzymatic and biological properties of new PLA 2 isoform from Crotalus durissus terrificus venom

Marcos Hikari Toyama

Toxicon, 2003

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Bothrops moojeni myotoxin-II, a Lys49-phospholipase A2 homologue: An example of function versatility of snake venom proteins

Rodrigo Stábeli

Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology, 2006

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Crystal structure of a novel myotoxic Arg49 phospholipase A2 homolog (zhaoermiatoxin) from Zhaoermia mangshanensis snake venom: Insights into Arg49 coordination and the role of Lys122 in the polarization of the C-terminus

Ulrich Kuch

Toxicon, 2008

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Crystal structure of a phospholipase A 2 homolog complexed with p-bromophenacyl bromide reveals important structural changes associated with the inhibition of myotoxic activity

Daniela Salvador

Biochimica Et Biophysica Acta-proteins and Proteomics, 2009

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The structure of the D49 phospholipase A2piratoxin III fromBothrops pirajaireveals unprecedented structural displacement of the calcium-binding loop: possible relationship to cooperative substrate binding

I. Polikarpov

Acta Crystallographica Section D Biological Crystallography, 2003

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Topology of the substrate-binding site of a Lys49-phospholipase A2 influences Ca2+-independent membrane-damaging activity

Roberto Ruller

Biochemical Journal, 2004

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At the interface: Crystal structures of phospholipases A2

Raghuvir Arni

Toxicon, 1998

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Structural Basis for the Inhibition of a Phospholipase A2-Like Toxin by Caffeic and Aristolochic Acids

Walter Cavalcante

PLOS ONE, 2015

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Structural bases for a complete myotoxic mechanism: crystal structures of two non-catalytic phospholipases A2-like from Bothrops brazili venom

Carlos Fernandes

Biochimica et biophysica acta, 2013

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Crystal structures of BnSP-7 and BnSP-6, two Lys49-phospholipases A2: quaternary structure and inhibition mechanism insights

Marcos Fontes

Biochemical and Biophysical Research Communications, 2003

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An overview of lysine-49 phospholipase A 2 myotoxins from crotalid snake venoms and their structural determinants of myotoxic action

Bruno Lomonte

Toxicon, 2003

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Computational BiologyProtein ScienceMacromolecular X-Ray Crystallogr...Biological SciencesPhylogenyCell lineMathematical SciencesMiceAnimalsProteinsSnake VenomBothropsStructure activity RelationshipStructure FunctionX Ray CrystallographyCytotoxinsMyotoxin A