Clostridium difficile Infections: The Continuous Challenge (original) (raw)

Clostridium difficile is a major cause of nosocomial diarrhea and pseudomembranous colitis, particularly following antibiotic treatment. This paper discusses the challenges associated with C. difficile infections, including the difficulty of recurrence due to spore resilience and disrupted gut microbiota. The review covers various treatment options, such as fecal microbiota transplantation (FMT), immunotherapies, and non-antibiotic strategies, highlighting the need for effective preventive measures and more research into treatment methodologies.