Validation of a triglyceride meter for use in pregnancy (original) (raw)
BMC research notes, 2014
Abstract
Elevated maternal triglycerides have been associated with adverse pregnancy outcomes including an increased risk of preeclampsia and macrosomia. A valid triglyceride meter would allow the examination of maternal postprandial triglycerides in a systematic manner. A non-fasting venous and two capillary measurements (using the Roche Accutrend® Plus meter) of triglycerides were measured in 40 participants at a mean of 36 weeks gestation. The two methods were highly correlated (r = 0.89, P < 0.0001), and the distributions were similar (mean difference 0.01 mmol/L (SD 0.47)), t = 0.18, P =0.86). Passing Bablok equation was: y = -0.01 + 0.98 × [95% CI intercept -0.51 - 0. 38; 95% CI slope 0.85-1.15). The estimated bias was -0.01 mmol/L (95% CI -0.93 - 0.91)). This study demonstrated the Accutrend® Plus meter provides results that correlate strongly with the reference method, with low bias, when used in late pregnancy.
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