SBSA as a New and Efficient Catalyst for the One-Pot Green Synthesis of Benzimidazole Derivatives at Room Temperature (original) (raw)

Benzimidazole Synthesis By Using Boron Sulfonic Acid As A New And Efficient Catalyst At Room Temperature

International Journal of ChemTech Research

Abstract: Boron sulfonic acid (BSA) was easily prepared and used as a new and efficient solid acid catalyst for the synthesis of benzimidazole derivatives with high isolated yields. Various substituted benzimidazoles were synthesized by a combination of o-phenylenediamines and aldehydes in the presence of boron sulfonic acid in with good yields in water and under a mild reaction conditions. This method is also applicable for precursors such as: aromatic and unsaturated aldehydes and o-phenylenediamines. Keywords: Boron sulfonic acid, BSA, solid acid, benzimidazole synthesis, green synthesis.

Boric Acid Catalyzed Convenient Synthesis of Benzimidazoles in Aqueous Media

Journal of Chemistry, 2013

Synthesis of benzimidazoles has been developed by theo-phenylenediamine with aldehydes using boric acid an efficient catalyst under mild reaction conditions in aqueous media. The product is applicable to aryl and heteroaryl aldehydes. This reaction led to the formation of benzimidazoles new derivatives in good yields. The FT-IR,19F-NMR,1H-NMR,13C-NMR spectra and elemental analysis confirm the structure of compounds.

Boric Acid Catalyzed Synthesis of Benzimidazoles in Aqueous Medium

2015

ABSTRACT: Water mediated green reaction of aromatic aldehyde with o-phenylenediamane in order to generate benzimidazoles using boric acid as a catalyst in water at room temperature furnished benzimidazoles in good yields. This protocol corresponds in short reaction time, low cost, high reaction yield

A Rapid Access to Novel and Known Benzimidazole Derivatives Using Silica Chloride as a Reusable Catalyst

A new application of silica chloride as an easily available and reusable solid acid catalyst for the synthesis of benzimidazole and its derivatives through the condensation of o-phenylenediamines and orthoesters under thermal and solvent-free conditions is described. This novel and eco-friendly method is very cheap and has many advantages including excellent yields, short reaction time, and simple work-up procedure.

Activated carbon sulfonic acid (AC-SO3H) as a green acidic catalyst for solvent-free synthesis of benzimidazole derivatives

2020

In this work, activated carbon sulfonic acid was prepared from the reaction of activated carbon and chlorosulfonic acid in chloroform at reflux conditions and characterized using X-ray powder diffraction (XRD) spectrum, infra-red (IR) spectrum, field emission scanning electron microscopy (FE-SEM) images and energy dispersive X-ray spectroscopy (EDS). Benzimidazole was prepared in excellent yields through the multicomponent condensation reaction of 1,2-phenylenediamine with aryl aldehydes in the presence of sulfonic acid-functionalized activated carbon (AC-SO3H), as an active catalyst, under solvent-free conditions. According to the optimized variables, the best reaction conditions for preparing benzimidazole were found to be: 0.02 gram of catalyst in solvent-free condition at 30 Min. and at 75 °C. To demonstrate the stability and durability of the catalyst, the yields of five successive runs with recovered catalyst were reported, showing no significant change in the obtained yields....

Dodecylbenzenesulfonic acid catalyzed one pot efficient synthesis of 2-substituted benzimidazole

2015

Synthesis of various benzimidazole derivatives by t he reaction of o-phenylene diamine with substituted benzaldehyde in presence of dodecylbenzenesulfonic acid as catal yst. The reaction is performed in ethanol-water at room temperature. Furthermore, a series of compounds we re synthesized and characterized by melting point, NMR and IR tools. The method was proved to be simple, conve nient, ecofriendly and product was isolated with go od yield.