Crystallographic studies of quadruplex nucleic acids (original) (raw)

Topology Conservation and Loop Flexibility in Quadruplex–Drug Recognition: Crystal Structures of Inter- and Intramolecular Telomeric DNA Quadruplex–Drug Complexes

Francisco Cuenca

Journal of Molecular Biology, 2008

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Structural Diversity and Specific Recognition of Four Stranded G-Quadruplex DNA

Sarika Saxena, Shrikant Kukreti

Current Molecular Medicine, 2011

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G-quadruplexes as targets for drug design

Elzbieta Izbicka

Pharmacology & …, 2000

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Quadruplex Ligands in Cancer Therapy

José García-Salcedo

Cancers, 2021

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DNA G-quadruplex and its potential as anticancer drug target

Buket Onel

Science China Chemistry, 2014

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Understanding Ligand Interaction with Different Structures of G-Quadruplex DNA: Evidence of Kinetically Controlled Ligand Binding and Binding-Mode Assisted Quadruplex Structure Alteration

Dev Verma

Analytical Chemistry, 2012

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Stabilizing parallel G-quadruplex DNA by a new class of ligands: Two non-planar alkaloids through interaction in lateral grooves

Qian Li

Biochimie, 2009

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Discovery of the first dual G-triplex/G-quadruplex stabilizing compound: a new opportunity in the targeting of G-rich DNA structures?

Jussara Amato

Biochimica et Biophysica Acta (BBA) - General Subjects, 2017

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Insights into the Small Molecule Targeting of Biologically Relevant G-Quadruplexes: An Overview of NMR and Crystal Structures

Domenica Musumeci

Pharmaceutics

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An Updated Focus on Quadruplex Structures as Potential Therapeutic Targets in Cancer

José García-Salcedo

International Journal of Molecular Sciences, 2020

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Common G-Quadruplex Binding Agents Found to Interact With i-Motif-Forming DNA: Unexpected Multi-Target-Directed Compounds

Bruno Pagano

Frontiers in chemistry, 2018

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Identification of novel telomeric G-quadruplex-targeting chemical scaffolds through screening of three NCI libraries

Anthony Reszka

Bioorganic & Medicinal Chemistry Letters, 2012

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The G quadruplex and its Ligands in anticancer therapy

kassam siddiq

G Quadruplex Ligands as a valid avenue for Anticancer Drug Development , 2019

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Quadruplex DNA: sequence, topology and structure

Alan Todd

Nucleic Acids Research, 2006

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Identification and Characterization of New DNA G-Quadruplex Binders Selected by a Combination of Ligand and Structure-Based Virtual Screening Approaches

Claudia Sissi

Journal of Medicinal Chemistry, 2013

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Interaction of G-Quadruplexes with Nonintercalating Duplex-DNA Minor Groove Binding Ligands

Akash jain

Bioconjugate Chemistry, 2011

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G-quadruplex structure of an anti-proliferative DNA sequence

ngoc do

Nucleic acids research, 2017

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DNA quadruplex : a potential target for anticancer therapy

Shilpa Borkar

2018

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State-of-the-Art Methodologies for the Discovery and Characterization of DNA G-Quadruplex Binders

Sandro Cosconati, Luigi Petraccone, Bruno Pagano, Concetta Giancola

Current Pharmaceutical Design, 2012

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Structure-Based Approaches Targeting Oncogene Promoter G-Quadruplexes

dik ma

Oncogene and Cancer - From Bench to Clinic, 2013

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Tailoring a lead-like compound targeting multiple G-quadruplex structures

Jussara Amato

European Journal of Medicinal Chemistry, 2018

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Targeting DNA G-Quadruplexes with Helical Small Molecules

Frédéric Godde

ChemBioChem, 2014

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G-Quadruplex targeting ligands: A hope and a new horizon in Cancer Therapeutics

Suman Panda

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Synthesis and Characterization of Monomolecular DNA G-Quadruplexes Formed by Tetra-End-Linked Oligonucleotides

Luigi Petraccone

Bioconjugate Chemistry, 2006

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Template-Assembled Synthetic G-Quadruplex (TASQ): A Useful System for Investigating the Interactions of Ligands with Constrained Quadruplex Topologies

Pascal Dumy, E. Defrancq

Chemistry - A European Journal, 2010

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Small-molecule quadruplex-targeted drug discovery

Mohan Kumar

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Exploring the Differential Recognition of DNA G-Quadruplex Targets by Small Molecules Using Dynamic Combinatorial Chemistry

Jean-Luc Wietor

Angewandte Chemie International Edition, 2008

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Biaryl polyamides as a new class of DNA quadruplex-binding ligands

Anthony Reszka

Chemical Communications, 2009

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