At the Roots of an Interdisciplinary Radical Innovation: Preliminary Insights from the Patenting Activity in the Bioinformatics Industry (original) (raw)

PATENTING BIOINFORMATICS INNOVATIONS: EMERGING TRENDS AND CHALLENGES IN THE UNITED STATES

Bioinformatics tools and techniques are useful not only to manage and analyze vast amount of raw biological data generated from various genomics research but also to understand the phenomena of biological system at the macromolecular level. The development of bioinformatics has come a long way from DNA sequencing tools of the Human Genome Project (HGP) era to DNA circuits and programmable synthetic biological devices in the twenty first century. The present article attempts to analyze and reveal the emerging trends in bioinformatics and computational biology research and innovation and challenges in patenting them under the current US patent regime.

A landscape of bioinformatics patents - Garnering of IPR in the field of bioinformatics

World Patent Information, 2017

In the current information technology era, Bioinformatics is growing rapidly due to availability of vast database systems and the ever increasing amount of biological data. It is a flexible and creative means of storing, managing, and querying of complex biological datasets. With these rapid advancements in today's technology-driven age, it is also imperative that protection in the form of Intellectual Property Rights (IPR) is sought for such research and development activity. In addition, there is a need to formulate an aggressive strategy to protect one's IP. In fact, various companies', universities', institutions' and researchers' are into the process to protect their core invention. This landscape will give an outline of the latest technological growth, geographical distribution, and top competitors playing an important role in this field.

Bioinformatics Innovation & Intellectual Property Rights

2020

Bioinformatics is an ever-growing field due to the availability of vast database systems and increasing biological data. This rapid development deals with research and development activities and requires adequate protection in the form of Intellectual Property Rights(IPR) as it adds value to the discoveries and provides incentives to the investors. The study includes the role of IPR in bioinformatics with a major focus on patents and related laws. The paper will also analyze, what type of bioinformatics are patentable, how does patent protect bioinformatics innovations specifically software which analyses DNA sequences. The paper will be presented in four parts namely, part one will consist of the introduction, while the part two will focus on what is bioinformatics and how it is related to IPR, part three will focus on the patent eligibility criteria for bioinformatics and lastly, part four will present a conclusion.

Patent Data for Comparative Study: Case study of Top Aspirants in Bioinformatics Industry

International Journal of Innovation

Innovation and technology are considered as a subject of success and achievement to the firm. The comparative study represents an essential procedure to identify the innovation and technological capabilities of major players involved in the bioinformatics related inventions. The aim of the research is to map out the top firms and identify their strategically important technologies. In view of this, the comparative analysis of major firms in bioinformatics industry is carried out using patent information. Herein the top three assignees are considered and based on this further analysis is performed. The top companies’ trend suggests that Thermo Fisher Scientific Inc. is the major player in bioinformatics research. Thus, we have tried to develop an overview on their patenting trend and important concerned areas of research. Also, our results indicate that the application of computational tools is being utilized for most of the research areas like the study of genomics and proteomics, s...

Validating Patent Indicators that Assess Technological Radicalness: The Case of Biotechnology

Technological innovations vary considerably in terms of novelty and impact with only a minority of new inventions contributing considerably to economic growth. More recently a number of patent-based indicators have been advanced to capture the different characteristics of technologically important inventions among which the notion 'radical' figures prominently. Radical inventions combine a high degree of novelty with a significant impact on future technology trajectories. Within this contribution, we compare and validate these indicators within the field of biotechnology. An extensive analysis of the recent history of biotechnology allows to identify important inventions (n=290) for the time period 1976 -2001. A considerable number of these inventions have been patented between 1976 and 2001 (n= 216; 75%). For all USPTO biotech patents filed between 1976 and 2001 (n= 84,119) relevant indicators have been calculated.

Patents, Citations and Innovations: Tracing the Links

1987

The goal is to tackle anew the main problems encountered in using patent data in economic research, namely, the large variance in the value of patents, and the difficulties in matching patents with economic categories. The first is addressed with the aid of patent citations, the second with computerized search techniques for large databases. The proposed solutions are applied to the case of Computed Tomography (CT) Scanners a pathbreaking innovation in medical technology. The main findings are that patents weighted by citations are highly correlated with the value of innovations, and that important innovations generate further innovative activity (R&D), and hence bring about down-the-line patents.

Evolving R&D Paradigms and Intellectual Property Strategies: A Historical Analysis across the Chemical, Biological, and Information Paradigms

PICMET '07 - 2007 Portland International Conference on Management of Engineering & Technology, 2007

As research in biology transitions from the chemical, to the biological paradigm, and now to the information-based (systems biology) paradigm, researchers should be aware of how such a transition is likely to interact with the existing patent regime. Such interactions critically affect investments in research and decisions relating to when to patent and what to patent. Practicing researchers both in the biological sciences and other scientific disciplines are increasingly facing the need to develop research and exploitation strategies in domains that are dynamic and complex. The traditional research addressing patent thickets and patent pools offers insufficient guidance with respect to new biological knowledge structures and their accompanying challenges.

Evolving R&D Paradigms and Intellectual Property Strategies: A Historical Analysis across the Chemical, Biological, and Information Paradigms

PICMET '07 - 2007 Portland International Conference on Management of Engineering & Technology, 2007

As research in biology transitions from the chemical, to the biological paradigm, and now to the information-based (systems biology) paradigm, researchers should be aware of how such a transition is likely to interact with the existing patent regime. Such interactions critically affect investments in research and decisions relating to when to patent and what to patent. Practicing researchers both in the biological sciences and other scientific disciplines are increasingly facing the need to develop research and exploitation strategies in domains that are dynamic and complex. The traditional research addressing patent thickets and patent pools offers insufficient guidance with respect to new biological knowledge structures and their accompanying challenges.

Determinants of patent citations in biotechnology: An analysis of patent influence across the industrial and organizational boundaries

Technological Forecasting and Social Change, 2015

The present paper extends the literature investigating key drivers leading certain patents to exert a stronger influence on the subsequent technological developments (inventions) than other ones. We investigated six key determinants, as (i) the use of scientific knowledge, (ii) the breadth of the technological base, (iii) the existence of collaboration in patent development, (iv) the number of claims, (v) the scope, and (vi) the novelty, and how the effect of these determinants varies when patent influence-as measured by the number of forward citations the patent received-is distinguished as within and across the industrial and organizational boundaries. We conducted an empirical analysis on a sample of 5671 patents granted to 293 US biotechnology firms from 1976 to 2003. Results reveal that the contribution of the determinants to patent influence differs across the domains that are identified by the industrial and organizational boundaries. Findings, for example, show that the use of scientific knowledge negatively affects patent influence outside the biotechnology industry, while it positively contributes to make a patent more relevant for the assignee's subsequent technological developments. In addition, the broader the scope of a patent the higher the number of citations the patent receives from subsequent non-biotechnology patents. This relationship is inverted U-shaped when considering the influence of a patent on inventions granted to other organizations than the patent's assignee. Finally, the novelty of a patent is inverted-U related with the influence the patent exerts on the subsequent inventions granted across the industrial and organizational boundaries.

Inventions shaping technological trajectories: do existing patent indicators provide a comprehensive picture?

2012

Since Schumpeter's seminal work on economic development (Schumpeter 1934), innovation is considered as one of the main drivers of firm performance and economic growth. At the same time, technological innovations vary considerably in terms of impact with only a minority of new inventions contributing significantly to economic growth. More recently a number of indicators derived from patent documents have been advanced to capture the nature and impact of technological inventions. Within this paper, we compare and validate these indicators within the field of biotechnology. An extensive analysis of the recent history of biotechnology allows us to identify the most important inventions (n=308) that shaped the field of biotechnology for the time period 1976-2001. A considerable number of these inventions have been patented between 1976 and 2001 (n= 215; 70%). For all USPTO biotech patents filed between 1976 and 2001 (n= 84,119) relevant indicators have been calculated. Within a next step, we assess which indicators allow to distinguish between most important patented inventions and their less influential counterparts by means of logistic regression models. Our findings reveal that the use of multiple, complementary, indicators provides the most comprehensive picture. In addition, it becomes clear that ex post indicators reflecting impact and value outperform ex ante indicators reflecting the nature and novelty of the invention in terms of precision and recall.