Respiratory Syncytial Virus Preterm (32-36 Completed Weeks Gestation) Risk Estimation Measure for RSV Hospitalization in Ireland: A Prospective Study (original) (raw)

The Pediatric infectious disease journal, 2015

Abstract

In several countries RSV prophylaxis is offered to late preterm infants who are at escalated risk of respiratory syncytial virus hospitalization (RSVH). However, targeted prophylaxis should be informed by country specific data. This study, which uniquely includes 36 weeks gestational age (GA) infants, aims to establish the risk factors for RSVH in 32-36 weeks GA infants in Ireland. A 13 hospital prospective observational study of laboratory confirmed RSVH in non-prophylaxed 32-36 weeks GA infants was conducted from July 2011- February 2014. Baseline and first year clinical data were analyzed using IBM SPSSV22. Significant (P<0.05) variables were entered into multiple logistic regression to determine independent risk factors for RSVH. Sixty-three percent of eligible infants (1,825/2,877) were recruited. The RSVH rate was 3.6 % (65/1807 analyzed infant records).There was no RSV attributable mortality. Twelve infants required intensive care. Of fifteen variables correlating to RSVH,...

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