Cannabis use, cognition and brain structure in first-episode psychosis (original) (raw)

AI-generated Abstract

Cannabis is the most widely used illegal substance, and its consumption is linked to a heightened risk of psychosis. However, the impact of cannabis on brain structure remains inadequately understood, given the inconsistent findings from previous studies. This research explores the relationship between cannabis use, cognitive performance, and cerebral architecture in individuals experiencing first-episode psychosis (FEP). It compares neuropsychological performance and brain morphology across three groups: patients with FEP who used cannabis, patients with FEP who did not, and healthy controls. The study's results indicate significant differences in cognitive tests and brain structure, emphasizing the need for further investigation into how cannabis affects cognitive function and neuroanatomy in psychosis.

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