Effects on guanine nucleotide and sulfhydryl reagent on subpopulations of muscarinic acetylcholine receptors in mammalian hearts: Possible evidence for interconversion of super-high and low affinity agonist binding sites (original) (raw)

Effects on guanine nucleotide and sulfhydryl reagent on subpopulations of muscarinic acetylcholine receptors in mammalian hearts: Possible evidence for interconversion of super-high and low affinity agonist binding sites

European Journal of Pharmacology, 1984

Abstract

Abstract Multiple site models of muscarinic acetylcholine receptors (mAChR) for agonist binding were applied to curves for the inhibition of QNB binding by carbachol by using nonlinear least square regression analysis. The effects of a guanine nucleotide guanyl-5 ...

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