Nuclear and Electron Spin Relaxation Techniques for delineation of bioinorganic and biological activities (original) (raw)

The paper discusses the application of nuclear and electron spin relaxation techniques in studying bioinorganic and biological systems. It highlights the historical context of magnetic resonance in biology, focusing on three main investigative approaches: conformational analysis of biomolecules, receptor-ligand interactions, and structural dynamics of metal-biomolecule complexes. Various NMR methodologies and their relevance in obtaining distance measurements in complex systems are elaborated, alongside the challenges encountered in analyzing paramagnetic metal complexes.