Metronomic Chemotherapy as a New Strategy for End-stage Pediatric Oncology Patients in Iran (original) (raw)

Metronomic chemotherapy offers a novel approach to treating end-stage pediatric oncology patients by continuously administering low doses of chemotherapy, focusing on inhibiting tumor angiogenesis. This method has shown promise in adult cancer treatment, but its application in pediatric patients in Iran is explored for the first time at Amir Oncology Hospital. New treatment regimens for various malignancies are proposed, underscoring the potential advantages of metronomic strategies in extending survival and improving quality of life for previously hopeless cases, while indicating the need for further optimization and research into specific drug combinations and mechanisms.