original ) (raw )The first 142 amino acids of glutamate decarboxylase do not contribute to epitopes recognized by autoantibodies associated with Type 1 diabetes
Kyla Chandler
Diabetic Medicine, 2018
View PDFchevron_right
Two amino acids in glutamic acid decarboxylase act in concert for maintainance of conformational determinants recognised by Type I diabetic autoantibodies
Anne-Marie Madec
Diabetologia, 2000
View PDFchevron_right
Recognition of Glutamic Acid Decarboxylase (GAD) by Autoantibodies from Different GAD Antibody-Positive Phenotypes
Åke Lernmark
2000
View PDFchevron_right
Demonstration of GAD-65 as the main immunogenic isoform of glutamate decarboxylase in type 1 diabetes and determination of autoantibodies using a radioligand produced by eukaryotic expression
Olle Kämpe
Journal of Clinical Investigation, 1993
View PDFchevron_right
Recognition of Glutamic Acid Decarboxylase (GAD) by Autoantibodies from Different GAD Antibody-Positive Phenotypes 1
Lisa Hammerle
The Journal of Clinical Endocrinology & Metabolism, 2000
View PDFchevron_right
Diabetic sera react with the glutamic acid decarboxylase molecule in a dimeric-oligomeric form
Merrill Rowley
Clinical and Experimental Immunology, 1996
View PDFchevron_right
Immune Reactivity of Diabetes-Associated Human Monoclonal Autoantibodies Defines Multiple Epitopes and Detects Two Domain Boundaries in Glutamate Decarboxylase
Fred Lühder
The Journal of Immunology
View PDFchevron_right
Detection of autoantibodies to the 65-kD isoform of glutamate decarboxylase by radioimmunoassay
Fred Lühder
European Journal of Endocrinology, 1994
View PDFchevron_right
Fine Mapping of Glutamate Decarboxylase 65 Epitopes Reveals Dependency on Hydrophobic Amino Acids for Specific Interactions
Gunnar Houen
International Journal of Molecular Sciences
View PDFchevron_right
Autoimmunity to two forms of glutamate decarboxylase in insulin-dependent diabetes mellitus
M. Clare-salzler
Journal of Clinical …, 1992
View PDFchevron_right
Characteristics of in-vitro phenotypes of glutamic acid decarboxylase 65 autoantibodies in high-titre individuals
Johnny Ludvigsson
Clinical & Experimental Immunology, 2013
View PDFchevron_right
The lack of anti-idiotypic antibodies, not the presence of the corresponding autoantibodies to glutamate decarboxylase, defines type 1 diabetes
Ingrid Kockum
Proceedings of the National Academy of Sciences, 2008
View PDFchevron_right
Antibodies to glutamic acid decarboxylase discriminate major types of diabetes mellitus
Merrill Rowley
Diabetes, 1992
View PDFchevron_right
“Masked” and overt autoantibodies specific to the DPD epitope of 65 kDa glutamate decarboxylase (GAD65-DPD) are associated with preserved beta cell functional reserve in Ketosis-Prone Diabetes
Lakshmi Gaur
The Journal of Clinical Endocrinology & Metabolism, 2014
View PDFchevron_right
Four IgG anti-islet human monoclonal antibodies isolated from a type 1 diabetes patient recognize distinct epitopes of glutamic acid decarboxylase 65 and are somatically mutated
Anne-Marie Madec
Journal of Immunology, 1996
View PDFchevron_right
Enzymatic characterization of a recombinant isoform hybrid of glutamic acid decarboxylase (rGAD67/65) expressed in yeast
Ian Mackay
Journal of Biotechnology, 2002
View PDFchevron_right
Glutamic acid decarboxylase 67-reactive T cells: a marker of insulin-dependent diabetes
Leonard Harrison
Journal of Experimental Medicine, 1993
View PDFchevron_right
Reactivity of islet cell antibodies (ICA) to recombinant glutamic acid decarboxylase (GAD)
Laura Guazzarotti
Journal of Autoimmunity, 1995
View PDFchevron_right
Development of 2 alternative enzyme-linked immunosorbent assays for routine screening of glutamic acid decarboxylase autoantibodies
Ruben Francisco Iacono
Clinica Chimica Acta, 2007
View PDFchevron_right
Characterization of self-glutamic acid decarboxylase 65-reactive CD4+ T-cell clones established from Japanese patients with insulin-dependent diabetes mellitus
Yasuharu Nishimura
Human Immunology, 1998
View PDFchevron_right
Sequence homology of the diabetes-associated autoantigen glutamate decarboxylase with coxsackie B4-2C protein and heat shock protein 60 mediates no molecular mimicry of autoantibodies
Bernd Schoel
Journal of Experimental Medicine, 1994
View PDFchevron_right
Immunization with the larger isoform of mouse glutamic acid decarboxylase (GAD67) prevents autoimmune diabetes in NOD mice
rahul singh
Diabetes, 1994
View PDFchevron_right
Antibody to the Mr 65,000 Isoform of Glutamic Acid Decarboxylase are Detected in Non-Insulin-Dependent Diabetes in Japanese
Alberto Falorni
Journal of Autoimmunity, 1996
View PDFchevron_right
Diagnostic sensitivity of immunodominant epitopes of glutamic acid decarboxylase (GAD65) autoantibodies in childhood IDDM
Carsten Carlberg
Diabetologia, 1996
View PDFchevron_right
Species and epitope specificity of two 65 kDa glutamate decarboxylase time-resolved fluorometric immunoassays
Christiane Hampe , Pieter E M Pauw
2007
View PDFchevron_right