A Trichodermin-Resistant Mutant of Saccharomyces cerevisiae with an Abnormal Distribution of Native Ribosomal Subunits (original) (raw)

This research explores a trichodermin-resistant mutant of Saccharomyces cerevisiae, focusing on its abnormal distribution of native ribosomal subunits. The study identifies the connection between this resistance and the 60-S ribosomal subunit's role in the binding of various antibiotics, revealing insights into potential molecular mechanisms involved in ribosomal function and resistance. Through various experimental setups, the findings suggest significant implications for understanding antibiotic resistance in eukaryotic organisms.