Laboratory Confirmation of Generalized Vaccinia following Smallpox Vaccination (original) (raw)

2004, Journal of Clinical Microbiology

The reinitiation of smallpox vaccination has renewed interest in implementing modern diagnostic methods to assess orthopoxvirus infection and adverse events following vaccination. We report here the laboratory confirmation of vaccinia virus in pustular lesions of a healthy adult vaccinee by use of a two-tier algorithm incorporating TaqMan PCR and electron microscopy.

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