Ascorbate does not protect macrophages against apoptosis induced by oxidised low density lipoprotein (original) (raw)

Physiologic levels of ascorbate inhibit the oxidative modification of low density lipoprotein

Atherosclerosis, 1990

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Selective macrophage ascorbate deficiency suppresses early atherosclerosis

Vladimir Babaev

Free Radical Biology and Medicine, 2011

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Potential Antiatherogenic Mechanisms of Ascorbate (Vitamin C) and a-Tocopherol (Vitamin E)

2000

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Potential Antiatherogenic Mechanisms of Ascorbate (Vitamin C) and -Tocopherol (Vitamin E)

Circulation Research, 2000

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Ascorbate Supplement Reduces Oxidative Stress in Dyslipidemic Patients Undergoing Apheresis

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Oxidized low density lipoprotein induces apoptosis via generation of reactive oxygen species in vascular smooth muscle cells

Cardiovascular Research, 2001

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Oxidation-sensitive mechanisms, vascular apoptosis and atherosclerosis

Trends in Molecular Medicine, 2003

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Human macrophages limit oxidation products in low density lipoprotein

Alexandra Krettek

Lipids in Health and Disease, 2005

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Myeloperoxidase-dependent caspase-3 activation and apoptosis in HL-60 cells: protection by the antioxidants ascorbate and (dihydro)lipoic acid

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Minimally Oxidized LDL Offsets the Apoptotic Effects of Extensively Oxidized LDL and Free Cholesterol in Macrophages

2010

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Vitamin C Protects Human Vascular Smooth Muscle Cells Against Apoptosis Induced by Moderately Oxidized LDL Containing High Levels of Lipid Hydroperoxides

Arteriosclerosis, Thrombosis, and Vascular Biology, 1999

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Oxidized Low-Density Lipoprotein Induces Macrophage Respiratory Burst via Its Protein Moiety: A Novel Pathway in Atherogenesis?

Thao Nguyen-khoa

Biochemical and Biophysical Research Communications, 1999

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Alteration in ascorbate and ascorbate peroxidase in programmed cell death and oxidative stress

ANNALISA PARADISO

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Oxidized LDL, homocysteine, homocysteine thiolactone and advanced glycation end products act as pro-oxidant metabolites inducing cytokine release, macrophage infiltration and pro-angiogenic effect in ARPE-19 cells

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Oxidative stress in atherogenesis: Basic mechanisms and problems of therapy with antioxidants

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Atherosclerosis and Current Anti-Oxidant Strategies for Atheroprotection

Current Trends in Atherogenesis, 2013

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A model of complex plaque formation: 7, 8-Dihydroneopterin protects human monocyte-derived macrophages from oxidised low density lipoprotein-induced death

2008

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Glycoxidation and lipid peroxidation of low-density lipoprotein can synergistically enhance atherogenesis

Hiroyuki Itabe, Noriyuki Sakata

Cardiovascular Research, 2001

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Oxidants and antioxidants in atherogenesis: an appraisal

Sumathi Ramachandran

Journal of Lipid Research, 1999

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Oxidized LDL triggers changes in oxidative stress and inflammatory biomarkers in human macrophages

Oscar Lara-Guzman

Redox biology, 2017

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Antioxidants and coronary artery disease

Andrea Poli, Alberico Catapano

Current Opinion in Lipidology, 1998

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Expression of Extracellular SOD and iNOS in Macrophages and Smooth Muscle Cells in Human and Rabbit Atherosclerotic Lesions : Colocalization With Epitopes Characteristic of Oxidized LDL and Peroxynitrite-Modified Proteins

Arteriosclerosis, Thrombosis, and Vascular Biology, 1998

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Increased macrophage glutathione content reduces cell-mediated oxidation of LDL and atherosclerosis in apolipoprotein E-deficient mice

Raymond Coleman

Atherosclerosis, 2002

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Ascorbate sustains neutrophil NOS expression, catalysis, and oxidative burst

Dr. Madhu Dikshit

Free Radical Biology and Medicine, 2008

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NAC Attenuates LPS-Induced Toxicity in Aspirin-Sensitized Mouse Macrophages via Suppression of Oxidative Stress and Mitochondrial Dysfunction

PLoS ONE, 2014

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Oxidized-LDL induce apoptosis in HUVEC but not in the endothelial cell line EA.hy 926

Atherosclerosis, 1999

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