CAD Performance Analysis for Pulmonary Nodule Detection: Comparison of Thick- and Thin-slice Helical CT Scans (original) (raw)

Abstract

PURPOSE To compare the performance of a computer-aided detection (CAD) system in detecting lung nodules from thick- and thin-slice helical CT scans, and to evaluate the potential benefit of CAD on radiologist sensitivity. METHOD AND MATERIALS Thoracic CT studies of 57 patients were used retrospectively to evaluate the potential contribution of a CAD system (QuickCue�, iCAD, Inc., Beavercreek, OH) in detecting lung nodules. All chest CT examinations were performed using a 4-detector LightSpeed QX/i scanner (GE Medical Systems, Milwaukee, WI). Images were obtained using the HQ setting with 5.0 mm collimation, helical pitch of 0.75/1.0, 120 kVp, and 160-270 mA. Images were then reconstructed with a slice thickness of 2.5 mm, providing thick-slice (5 mm) and thin-slice (2.5mm) scans for each patient. Two board-certified radiologists reviewed the thick-slice studies and all identified nodules were documented. The CAD system was then applied to both the thick-slice and thin-slice studies ...

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